Evidence map›Paper›PMID 41270021›Full record

ArticlePloS one2025

Association between dietary intake of protein and amino acids and sarcopenia: a cross-sectional study.

Weixia Yuan, Panpan Ao, Yun Ma, Ying Ma, Juan Song, Shaofeng Wei, Lijia Yuan

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Weixia YuanSchool of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Panpan AoSchool of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Yun MaSchool of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Ying MaDepartment of Nutrition, Joint Logistics Support Force 925th Hospital, Guiyang, Guizhou, China.
Juan SongDepartment of Nutrition, Joint Logistics Support Force 925th Hospital, Guiyang, Guizhou, China.
Shaofeng WeiSchool of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.
Lijia YuanSchool of Public Health, Guizhou Medical University, Guiyang, Guizhou, China.ORCID https://orcid.org/0009-0006-4223-1511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo research the effects of diet on sarcopenia, and to examine the association of protein and amino acid sources with the risk of sarcopenia in older adults.

methodsFrom December 2023 to July 2024, 84 patients with sarcopenia and 173 without sarcopenia were included in the study at the Joint Logistics Support Force 925th Hospital. We compared the in diet and general characteristics between the two groups. Multivariate logistic regression analysis was performed to assess the effects of total protein, animal protein, plant protein, and amino acid on the risk of sarcopenia in older adults.

resultsIn terms of nutrient intake, the dietary intakes of energy, protein, fat, carbohydrates, and dietary fiber were significantly lower in the sarcopenia group than the non-sarcopenia group (P < 0.05). Analysis of protein showed that the highest tertile of total protein and animal protein intake was associated with lower incident sarcopenia risk (P < 0.05), while plant protein intake showed no significant association. Further analysis of amino acid showed that the highest tertile of leucine, glutamate, cystine, and tyrosine intake was associated with increased risk of sarcopenia, whereas arginine intake was linked to a lower incident sarcopenia risk (OR: 0.442, 95% CI: 0.200 ~ 0.979; P-trend = 0.038).

conclusionsThe insufficient intake of animal protein and amino acids may be closely associated with the risk of sarcopenia in older adults. Moderately increasing the intake of arginine and animal protein may help reduce the risk of sarcopenia in older adults.

Indexed as

Amino AcidsDietary ProteinsSarcopeniaAgedAged, 80 and overCross-Sectional StudiesDietFemaleHumansMaleMiddle AgedRisk FactorsAmino AcidsDietary Proteins

Identifiers

PMID41270021
PMCPMC12637923

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.