Trial reportPloS one2025
Effects of varying exercise intensities on muscle strength and depressive symptoms in Chinese adolescents: A 12-week randomized controlled trial.
Trial report in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Exercise as a multimodal intervention for adolescent depression: integrating neuroplasticity, BDNF signaling, stress biomarkers, exercise intensity, digital mental health interventions, and precision psychiatry.Frontiers in psychiatry · 2026Review
- Can exercise truly alleviate mild-to-moderate and subthreshold depression? Evidence from randomized controlled trials.Frontiers in psychology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study investigates the effects of physical education programs with varying exercise intensities on muscle strength and depressive symptoms in adolescents, while also evaluates the role of muscle strength improvement in alleviating depressive symptoms. A total of 266 eighth-grade students were divided into three groups based on exercise intensity (low, moderate, and vigorous). Over 12 weeks, students participated in physical education sessions three times per week. Muscle strength was assessed using the standing long jump and handgrip strength tests, while depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale (CES-D). Paired t-tests and one-way ANOVA were used to evaluate intra-group and inter-group differences, respectively. Multiple linear regression analysis was conducted to examine the predictive effect of muscle strength changes on depressive symptoms. Results indicated Significant improvements in standing long jump and grip strength were observed across all groups, with the vigorous-intensity group achieving the greatest gains. Depressive symptoms improved significantly in the moderate- and vigorous-intensity groups, with the latter showing the most pronounced reductions. Notably, improvements in standing long jump significantly predicted reductions in depressive symptoms, particularly in the vigorous-intensity group, whereas handgrip strength did not. These results suggest that integrating higher-intensity physical activities into school programs may have beneficial effects on both physical and mental health. Lower-limb muscle strength improvements predict reduced depressive symptoms, underscoring the importance of targeted strength training in physical education. This clinical trial has been registered with the Chinese Clinical Trial Registry under the registration number ChiCTR2500103874.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.