ArticleJournal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG2026
Real-world management of adjuvant systemic melanoma therapy: Multi-center survey of 51 DeCOG skin cancer centers.
Article in Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Lorlatinib and neurocognitive adverse events: characterization, risk factors, and the potentially mitigative role of social support.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
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12 authors.
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Abstract
backgroundAdjuvant immune checkpoint inhibitors (ICI) and targeted therapy (TT) have revolutionized treatment management for patients with melanoma. However, the current German S3 guideline does not differentiate between patients with and without adjuvant therapy in its recommendations for imaging intervals and follow-up monitoring, leading to variability in clinical practice. This study provides an overview of surveillance practices among skin cancer centers in the German Dermatologic Cooperative Oncology Group (DeCOG).
methodsA survey was sent to 80 skin cancer centers in Germany, Austria and Switzerland on November 22, 2023. Responses received by March 10, 2024 were analyzed descriptively.
resultsFifty-one responses (64%) were received. Forty centers (78%) reported deviations from the guideline. In stage IIB, 34 centers (67%) conduct imaging including CT scans prior to and after adjuvant therapy. Post-adjuvant therapy, 36 centers (71%) conduct imaging according to the guideline. Over 90% of the centers offer adjuvant ICI therapy if progression occurs on adjuvant TT and vice versa. In stage IV, after relapse while on adjuvant ICI, 32 centers (63%) would offer adjuvant TT.
conclusionsSurveillance practices differed among participating centers and often do not align with the current guideline. A consensus based consistent approach would benefit both patients and physicians.
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