Evidence map›Paper›PMID 41273404›Full record

SynthesisEuropean child & adolescent psychiatry2026

Neurophysiological alterations during sensory processing in autism - a meta-analysis.

Anjuli Ghosh, Natalia Nasarre-Nacenta, Sarah Baumeister, Nathalie E Holz, Tobias Banaschewski, Daniel Brandeis, Pascal-M Aggensteiner, Anna Kaiser

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European child & adolescent psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anjuli Ghosh *Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, J 5 · 68159, Germany. Anjuli.Ghosh@zi-mannheim.de.ORCID http://orcid.org/0009-0006-9138-0177
Natalia Nasarre-Nacenta *Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, J 5 · 68159, Germany.
Sarah BaumeisterDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, J 5 · 68159, Germany.ORCID http://orcid.org/0000-0001-9005-0084
Nathalie E HolzDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, J 5 · 68159, Germany.ORCID http://orcid.org/0000-0002-6225-9267
Tobias BanaschewskiDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, J 5 · 68159, Germany.ORCID http://orcid.org/0000-0003-4595-1144
Daniel BrandeisDepartment of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, J 5 · 68159, Germany.
Pascal-M Aggensteiner *Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, J 5 · 68159, Germany.ORCID http://orcid.org/0000-0002-1048-9044
Anna Kaiser *Department of Child and Adolescent Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, J 5 · 68159, Germany.ORCID http://orcid.org/0009-0001-6373-8278

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While sensory processing alterations in autism are well-documented, the neurophysiological correlates remain unclear. This meta-analysis examined differences in early event-related potentials (ERP) and event-related fields (ERF) between autistic and non-autistic individuals using electroencephalography and magnetoencephalography to identify neurophysiological alterations that may underlie variations in sensory perception, communication, and social interaction in autism. Following PRISMA guidelines, a database search was conducted for peer-reviewed studies published from January 1980 onwards. Random-effects meta-analyses were performed using the metafor package in R. Standardised mean-group differences in early ERP/ERF latencies and amplitudes were analysed with moderator analyses exploring demographic and methodological factors, including neurophysiological technique, sensory modality, age group, sex, and language impairment. 145 studies (3778 autistic, 3484 non-autistic participants) were included. Autistic individuals exhibited significantly longer latencies in P/M50 (SMD = 0.44; SE = 0.21; 95% CI 0.03-0.86; p = 0.04), P/M100 (SMD = 0.18; SE = 0.08; 95% CI 0.01-0.36; p = 0.03), N170 (SMD = 0.33; SE = 0.12; 95% CI 0.10-0.56; p = 0.01), and P/M200 (SMD = 0.30; SE = 0.09; 95% CI 0.12-0.48; p = 0.00) components. P/M50 showed the greatest latency alteration, with an effect-size nearing medium, especially in individuals with language impairment (Q

Indexed as

Autistic DisorderEvoked PotentialsChildElectroencephalographyHumansMagnetoencephalographyAutismElectroencephalographyMagnetoencephalographyMeta-analysisNeurophysiologySensory processing

Identifiers

PMID41273404
PMCPMC13212416

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.