Evidence map›Paper›PMID 41273503›Full record

ArticleJournal of nephrology2025

Pregnancy after kidney transplantation: global insights based on registry data from three continents.

Styliani Giapoutzidou, Erandi Hewawasam, Margriet E Gosselink, A Titia Lely, Michael J Moritz, Serban Constantinescu, Lisa Coscia, Shilpanjali Jesudason, Margriet F C de Jong

Abstract readComparative Study
In one paragraph

Article in Journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Styliani GiapoutzidouDepartment of Nephrology, University Medical Center Groningen, Groningen, Netherlands. s.giapoutzidou@umcg.nl.ORCID 0009-0006-8996-6347
Erandi HewawasamAustralia and New Zealand Dialysis and Transplant Registry, South Australian Health and Medical Research Institute, Adelaide, Australia.
Margriet E GosselinkDepartment of Obstetrics and Gynecology, University Medical Center Utrecht, Utrecht, Netherlands.
A Titia LelyDepartment of Obstetrics and Gynecology, University Medical Center Utrecht, Utrecht, Netherlands.
Michael J MoritzTransplant Pregnancy Registry International, Gift of Life Institute, Philadelphia, PA, USA.
Serban ConstantinescuTransplant Pregnancy Registry International, Gift of Life Institute, Philadelphia, PA, USA.
Lisa Coscia *Transplant Pregnancy Registry International, Gift of Life Institute, Philadelphia, PA, USA.
Shilpanjali Jesudason *Australia and New Zealand Dialysis and Transplant Registry, South Australian Health and Medical Research Institute, Adelaide, Australia.
Margriet F C de Jong *Department of Nephrology, University Medical Center Groningen, Groningen, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLack of data regarding pregnancy post-kidney transplantation challenges clinicians who are faced with complex, high-risk cases. Aiming at tackling knowledge gaps and limited cross-cultural data on pregnancy in kidney transplant recipients (KTRs), we compared the methodologies and pregnancy outcomes of three registries based in three continents.

methodsData were gathered from reports and publications of the Pregnancy After Renal Transplantation OUTcomes registry (PARTOUT, Netherlands), the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA), and the Transplant Pregnancy Registry International (TPRI, United States of America and international). We targeted the similarities and differences among the registries to understand methodological variations.

resultsThe registries utilized distinct approaches regarding data collection which influence data interpretation. PARTOUT conducted a retrospective analysis of all Dutch pregnant KTRs between 1971 and 2017. ANZDATA includes annual surveys on all KTR parenthood events since 1968. TPRI offers international coverage and includes pregnant KTRs voluntarily registered since 1991. Despite methodological differences, preeclampsia, preterm birth and low birth weight were common pregnancy complications, and outcomes were mostly comparable among the registries.

conclusionsDespite differences in case capture, the three registries reported similar pregnancy and newborn outcomes, confirming that pregnancy in KTRs can be successful with careful monitoring across varying populations. Identifying the strengths and weaknesses of each registry can contribute to improved methodologies for global data collection and lower missing data rates. Although managing large databases may be challenging, aligning data across countries could lead to meaningful data pooling, while identifying drivers of outcomes across subpopulations.

Indexed as

Kidney TransplantationPregnancy ComplicationsAdultAustraliaFemaleHumansInfant, Low Birth WeightInfant, NewbornNetherlandsNew ZealandPregnancyPregnancy OutcomePremature BirthRegistriesRetrospective StudiesRisk FactorsKidney diseaseMethodologyPregnancyRegistryTransplantation

Identifiers

PMID41273503
PMCPMC12711958

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.