Evidence map›Paper›PMID 41273512›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2026

Preparative Chiral Resolution of Synthetic Cathinones Using Polysaccharide-Based Chiral Stationary Phases.

Tereza Maříková, Ghaid W A Abualzulof, Bronislav Jurásek, Michal Kohout

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Article in Methods in molecular biology (Clifton, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tereza MaříkováForensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Prague, Czech Republic.
Ghaid W A AbualzulofDepartment of Pharmaceutical Sciences, University of Perugia, Perugia, Italy.
Bronislav JurásekForensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Prague, Czech Republic.
Michal KohoutDepartment of Organic Chemistry, University of Chemistry and Technology Prague, Prague, Czech Republic. michal.kohout@vscht.cz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic cathinones represent one of the largest groups of new psychoactive substances (NPS), compounds that are being distributed as temporarily legal alternatives to illicit drugs. Apart from this aspect, synthetic cathinones have been intensively studied for their potential medicinal use. Hereby, we discuss some basic considerations for their chiral resolution, which enables the assessment of the biological effect of the individual enantiomers of these drugs. The examples illustrate the utilization of two versatile polysaccharide-based chiral stationary phases (CSPs) in different mobile phases (MPs). Protocols for easy and scalable harvesting of the separated enantiomers are also provided.

Indexed as

AlkaloidsPolysaccharidesPsychotropic DrugsChromatography, High Pressure LiquidStereoisomerismSynthetic CathinoneAlkaloidscathinonePolysaccharidesPsychotropic DrugsSynthetic CathinoneAmyloseCelluloseEnantioseparationPolysaccharide-based chiral stationary phasePreparative chiral resolutionSynthetic cathinones

Identifiers

PMID41273512

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.