Evidence map›Paper›PMID 41275451›Full record

ReviewDiscover oncology2025

CEBPB emerges as a key regulatory factor in human cancers through diverse molecular mechanisms and clinical implications.

Anbang He, Cunjin Wu, Dan Xia, Yi Zhu

Abstract readReview
In one paragraph

Review in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anbang He *Department of Urology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 311121, China. heanbang323@163.com.
Cunjin Wu *Department of Urology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 311121, China.
Dan XiaDepartment of Urology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 311121, China. xiadan@zju.edu.cn.
Yi ZhuDepartment of Urology, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 311121, China. urozy@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CCAAT/enhancer-binding protein beta (CEBPB) is a critical transcription factor for cellular differentiation, inflammation, and metabolism. Recent studies have highlighted its dual role in tumorigenesis, functioning as both an oncogenic driver and tumor suppressor across diverse malignancies. This review synthesizes advances in understanding CEBPB's contributions to tumorigenesis, tumor progression, immune evasion, and therapy resistance, emphasizing its potential as a cancer-specific molecular biomarker in cancer diagnosis, prognosis and treatment.

Indexed as

Anticancer drugCancerCancer therapyCCAAT/enhancer-binding protein betaCEBPBSmall-molecule compoundsTherapeutic target

Identifiers

PMID41275451
PMCPMC12748389

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.