Evidence map›Paper›PMID 41277169›Full record

ArticleCancer control : journal of the Moffitt Cancer Center

Treatment Outcome and Associated Factors Among Women With Gestational Trophoblastic Neoplasia in Northwest Ethiopia: A Multi-Center Retrospective Cohort Study.

Abel Temeche Kassaw, Mekuanent Kassa Birarra, Ephrem Tafesse Teferi, Eliyas Adissu Taye, Desalegn Addis Mussie, Fisseha Nigussie Dagnew, Getachew Yitayew Tarekegn, Samuel Berihun Dagnew, Tilaye Arega Moges, Belayneh Yitayew Wallie and 2 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abel Temeche KassawDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0009-0008-3431-8187
Mekuanent Kassa BirarraDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Ephrem Tafesse TeferiDepartment of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Eliyas Adissu TayeDepartment of Health Informatics, School of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Desalegn Addis MussieDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Fisseha Nigussie DagnewDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
Getachew Yitayew TarekegnDepartment of Clinical Pharmacy, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Samuel Berihun DagnewDepartment of Clinical Pharmacy, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Tilaye Arega MogesDepartment of Clinical Pharmacy, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.
Belayneh Yitayew WallieDepartment of Pharmacy, College of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia.
Woretaw Sisay ZewduDepartment of Pharmacology and Toxicology, Pharmacy Education and Clinical Services, Debre Tabor University, Debre Tabor, Ethiopia.ORCID 0000-0003-2616-4014
Tigabu Eskeziya ZerihunDepartment of Clinical Pharmacy, Pharmacy Education and Clinical Services Directorate, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionGestational trophoblastic neoplasia (GTN) is the most curable gynecologic malignancy. However, resistance to first-line chemotherapy remains common, and mortality is high in developing countries.ObjectiveTo evaluate remission, relapse, survival, and associated factors among GTN patients in northwest Ethiopia.MethodsA hospital-based, multi-center retrospective cohort study was conducted on 205 patients treated between August 1, 2019, and July 31, 2024. Data were collected from medical charts and phone interviews. Logistic regression identified factors affecting remission. Kaplan-Meier analysis was used to estimate the overall survival (OS) probabilities. Prognostic factors were determined using Cox regression. Results were interpreted as adjusted odds (AOR) and adjusted hazard ratios (AHR) with 95% confidence intervals. Statistical significance was declared at

Indexed as

Gestational Trophoblastic DiseaseAdolescentAdultDrug Resistance, NeoplasmEthiopiaFemaleHumansMiddle AgedNeoplasm Recurrence, LocalPregnancyPrognosisRetrospective StudiesTreatment OutcomeYoung Adultand northwest Ethiopiaassociated factorschemotherapychemotherapy resistancegestational thromboplastic neoplasiamortality ratetreatment outcome

Identifiers

PMID41277169
PMCPMC12644429

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.