Evidence mapPaperPMID 41277234Full record

ReviewGut microbes2025

Gut microbiota dysbiosis at the interface of neuropsychiatric disorders and their dermatological comorbidities.

Brittany Hawkins, Maddison Montgomery, Gabriela Bokota, Maria Santoyo, Erica Giron, Ahmed Eltokhi

Abstract readReview
In one paragraph

Review in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Oxidative and Nitrosative Stress in Atopic Dermatitis and Depression: Similarities in Biomarkers and Pathophysiological Mechanisms.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Gut microbial biomarkers for major depressive disorder: a cross-sectional study.Frontiers in cellular and infection microbiology · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brittany HawkinsSchool of Medicine, Mercer University, Columbus, GA, USA.ORCID 0009-0005-4546-2449
Maddison MontgomerySchool of Medicine, Mercer University, Columbus, GA, USA.
Gabriela BokotaSchool of Medicine, Mercer University, Columbus, GA, USA.
Maria SantoyoSchool of Medicine, Mercer University, Columbus, GA, USA.
Erica GironSchool of Medicine, Mercer University, Columbus, GA, USA.
Ahmed EltokhiSchool of Medicine, Mercer University, Columbus, GA, USA.ORCID 0000-0001-9067-5017

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuropsychiatric disorders such as autism spectrum disorder (ASD), generalized anxiety disorder (GAD), major depressive disorder (MDD), and schizophrenia (SZ) frequently co-occur with dermatological conditions, including atopic dermatitis, psoriasis, rosacea, and chronic urticaria. The biologic basis remains incompletely understood. A growing body of evidence implicates gut microbiota dysbiosis as a shared pathogenic factor linking these conditions. This review synthesizes preclinical and clinical findings demonstrating consistent microbial alterations across both neuropsychiatric and dermatologic conditions, including fluctuations in alpha diversity, disrupted Firmicutes/Bacteroidetes ratios, and depletion of short-chain fatty acid (SCFA)-producing taxa such as

Indexed as

DysbiosisGastrointestinal MicrobiomeMental DisordersSkin DiseasesAnimalsBacteriaComorbidityHumansdermatological comorbiditiesgut–brain–skin axisGut microbiota dysbiosisneuropsychiatric disordersprobiotics

Identifiers

PMID41277234
PMCPMC12645903

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.