Evidence mapPaperPMID 41278193Full record

ReviewFrontiers in cell and developmental biology2025

Extracellular vesicles in laboratory medicine: a review and outlook.

Xingdong Wang, Meijin Liu, Minghong Zhao, Haibin Shen, Qing Jin, Dingyu Rao, Defa Huang

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xingdong Wang *Department of Pharmacy, Aerospace Center Hospital, Beijng, China.
Meijin Liu *Laboratory Medicine, People's Hospital of Ganzhou Economic Development Zone, Ganzhou, China.
Minghong Zhao *Laboratory Medicine, Guizhou Aerospace Hospital, Zunyi, China.
Haibin ShenLaboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Qing JinLaboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Dingyu RaoDepartment of Cardiothoracic Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Defa HuangLaboratory Medicine, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs), serving as promising novel biomarkers for diseases, demonstrate extensive potential applications in disease diagnosis, prognosis evaluation, and treatment monitoring. Currently, EVs have made substantial advancements in the areas of disease diagnosis, prognosis, and treatment. Nevertheless, for EVs to be fully integrated into clinical laboratories, ongoing efforts are required in multi-omics integration and big data analysis, the development of clinically applicable separation and detection technologies, the establishment of standardized quality systems, as well as clinical trials and regulatory approval processes. This paper reviews the current status of the application of extracellular vesicles in disease diagnosis, prognostic assessment, and treatment monitoring, analyzes the challenges facing current research, and discusses future trends.

Indexed as

development trendsdisease diagnosisextracellular vesicleslaboratory medicineprognostic evaluation

Identifiers

PMID41278193
PMCPMC12631457

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.