Evidence mapPaperPMID 41278569Full record

ArticleFrontiers in veterinary science2024

Dietary supplementation of nucleotides and oligosaccharides in kittens reduces the expression of circulating miR-1-3p, miR-133a-3p, miR-206-3p and miR-383-5p.

Fabio Albanese, Matthew Harrison, Michelle J Farquhar, Lucy J Holcombe, Jujhar Atwal, Phil Watson, Anna M Piccinini

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fabio AlbaneseWALTHAM Petcare Science Institute, Melton Mowbray, Leicestershire, United Kingdom.
Matthew HarrisonWALTHAM Petcare Science Institute, Melton Mowbray, Leicestershire, United Kingdom.
Michelle J FarquharWALTHAM Petcare Science Institute, Melton Mowbray, Leicestershire, United Kingdom.
Lucy J HolcombeWALTHAM Petcare Science Institute, Melton Mowbray, Leicestershire, United Kingdom.
Jujhar AtwalWALTHAM Petcare Science Institute, Melton Mowbray, Leicestershire, United Kingdom.
Phil WatsonWALTHAM Petcare Science Institute, Melton Mowbray, Leicestershire, United Kingdom.
Anna M PiccininiSchool of Pharmacy, University of Nottingham, Nottingham, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune system of kittens is less efficient at fighting pathogens compared to adult cats with kittens being more susceptible to infections. Increasing evidence shows that dietary interventions can enhance immunity in mammals and modulate the expression of microRNAs (miRNAs) with key immune functions, however research in kittens is limited. Diets that can enhance the ability of a kitten's developing immune system to successfully fight infections, and where effects can be monitored by veterinarians, are highly sought-after. Here, we utilised small RNA sequencing (RNA-Seq) to investigate the effects of an experimental (test) diet containing nucleotides and oligosaccharides on the global expression of circulating miRNAs in 23-week-old kittens (

Indexed as

biomarkerdevelopmentfelineFOSimmunemicroRNAnucleotideXOS

Identifiers

PMID41278569
PMCPMC12632807

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.