Evidence map›Paper›PMID 41278648›Full record

ArticlebioRxiv : the preprint server for biology2025

Hierarchical regulation of cerebellar neurogenesis by Sin3A-mediated gene repression.

Lei Chen, Ankita Roy, Gregory David, Chin Chiang

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lei ChenDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, 4114 MRB III, Nashville, TN 37232.
Ankita RoyDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, 4114 MRB III, Nashville, TN 37232.
Gregory DavidDepartment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, East Tower, 935, New York, NY 10016.
Chin ChiangDepartment of Cell and Developmental Biology, Vanderbilt University School of Medicine, 4114 MRB III, Nashville, TN 37232.

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
Regulatory mechanisms of cerebellar lineage developmentR01NS131495 · NINDS · VANDERBILT UNIVERSITY · PI CHIN CHIANG · 2024 to 2026
$1.7M
Regulatory mechanisms of cerebellar lineage developmentR56NS131495 · NINDS · VANDERBILT UNIVERSITY · PI CHIANG, CHIN · 2023 to 2023
$555k
NCI NIH HHS P30 CA068485NINDS NIH HHS R01 NS131495NINDS NIH HHS R56 NS131495
6 · The paper itself

Abstract

Cerebellar granule cells (GCs) are critical for motor and cognitive functions. Lineage tracing studies have identified a hierarchical developmental progression of GC neurogenesis, transitioning from Sox2

Indexed as

Atoh1cerebellar granule cellsdifferentiationepigenetic regulationNeuroD1Sin3ASox2

Identifiers

PMID41278648
PMCPMC12632768

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.