Evidence map›Paper›PMID 41278665›Full record

ArticlebioRxiv : the preprint server for biology2025

Glial cell-intrinsic and non-cell autonomous toxicity in a Drosophila C9orf72 neurodegeneration model.

I Hubbard, J Dubnau

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

I HubbardProgram in Neuroscience, Department of Neurobiology and Behavior, Stony Brook University, NY 11794, USA.ORCID 0009-0003-1029-5156
J DubnauProgram in Neuroscience, Department of Neurobiology and Behavior, Stony Brook University, NY 11794, USA.ORCID 0000-0002-9285-7444

Funding

Feedback amplification between Retrotransposons/endogenous retroviruses and TDP-43 in Alzheimers related dementiasR01AG078788 · NIA · STATE UNIVERSITY NEW YORK STONY BROOK · PI JOSHUA T DUBNAU · 2022 to 2026
$3.8M
Brain aging and Alzheimer's related dementias: convergence onto retrotransposons and endogenous retrovirusesR01AG076493 · NIA · STATE UNIVERSITY NEW YORK STONY BROOK · PI JOSHUA T DUBNAU · 2025 to 2026
$1.1M
NIA NIH HHS R01 AG076493NIA NIH HHS R01 AG078788
6 · The paper itself

Abstract

The most common genetic cause of both familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) is an expanded G

Identifiers

PMID41278665
PMCPMC12632525

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.