Evidence map›Paper›PMID 41278732›Full record

ArticlebioRxiv : the preprint server for biology2025

Leveraging CRISPR-Cas13d in an inducible knockdown system to interrogate

Zoya A Gauhar, Aaron J Duthoy, Seema Chatterjee, Rodrigo Berber-Pulido, Cameron Myhrvold, Elizabeth R Gavis

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zoya A GauharDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, 08540.
Aaron J DuthoyDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, 08540.
Seema ChatterjeeDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, 08540.
Rodrigo Berber-PulidoDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, 08540.
Cameron MyhrvoldDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, 08540.ORCID 0000-0002-8971-184X
Elizabeth R GavisDepartment of Molecular Biology, Princeton University, Princeton, New Jersey, 08540.

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007388 · NIGMS · PRINCETON UNIVERSITY · PI CRISTEA, ILEANA M. · 1985 to 2022
$27.4M
Mechanisms of mRNA localization and translational control in Drosophila developmentR35GM126967 · NIGMS · PRINCETON UNIVERSITY · PI ELIZABETH R GAVIS · 2018 to 2026
$5.9M
Development of a highly-multiplexed CRISPR-based TB drug susceptibility testR01AI182281 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Cameron Amadeus Myhrvold, Yingda Linda Xie · 2024 to 2026
$2.2M
NIAID NIH HHS R01 AI182281NIGMS NIH HHS R35 GM126967NIGMS NIH HHS T32 GM007388
6 · The paper itself

Abstract

Ribonucleoprotein (RNP) germ granules are hallmarks of germ cells across the animal kingdom and are thought to be hubs for post-transcriptional regulation that promote formation of the germ cell precursors. While numerous RNAs are associated with germ granules in

Identifiers

PMID41278732
PMCPMC12636468

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.