Evidence mapPaperPMID 41279030Full record

ArticlebioRxiv : the preprint server for biology2025

Comparative analysis of single-stranded and non-canonical DNA formation in human and other ape cells with telomere-to-telomere genomes.

Jacob Sieg, Huiqing Zeng, Hana Pálová, Linnéa Smeds, Saswat Mohanty, Angelika Lahnsteiner, Francesca Chiaromonte, Kateryna D Makova

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacob SiegDepartment of Biology, Penn State University, University Park, PA, USA.ORCID 0000-0001-5414-1667
Huiqing ZengDepartment of Biology, Penn State University, University Park, PA, USA.
Hana PálováDepartment of Biology, Penn State University, University Park, PA, USA.ORCID 0000-0001-8803-9433
Linnéa SmedsDepartment of Biology, Penn State University, University Park, PA, USA.ORCID 0000-0002-8415-9259
Saswat MohantyDepartment of Biology, Penn State University, University Park, PA, USA.ORCID 0000-0002-1813-589X
Angelika LahnsteinerDivision of Cancer (Epi-)Genetics, Department of Biosciences and Medical Biology, Center for Tumor Biology and Immunology (CTBI), Paris Lodron University Salzburg, Salzburg, Austria.ORCID 0000-0001-7402-3369
Francesca ChiaromonteDepartment of Statistics, Penn State University, University Park, PA, United States.
Kateryna D MakovaDepartment of Biology, Penn State University, University Park, PA, USA.ORCID 0000-0002-6212-9526

Funding

Non-B DNA and Genome EvolutionR35GM151945 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · 2024 to 2025
$1.7M
NIGMS NIH HHS R35 GM151945
6 · The paper itself

Abstract

Non-canonical (non-B) DNA secondary structures, e.g., G-quadruplexes and triplex DNA, are mutation hotspots and genome regulators contributing to disease and evolution. Yet they remain uncharacterized in complete genomes

Identifiers

PMID41279030
PMCPMC12637528

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.