Evidence map›Paper›PMID 41279439›Full record

ArticlebioRxiv : the preprint server for biology2025

A chromatin-associated pool of Aurora A controls kinetochore-microtubule attachments to ensure chromosome biorientation.

Johnathan L Meaders, Alyssa A Rodriguez, Smriti Variyar, SungWoo Park, Alessandro E Cirulli, Karen Oegema, Kevin D Corbett, Arshad Desai

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Johnathan L MeadersDepartment of Cell & Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA.
Alyssa A RodriguezDepartment of Cellular & Molecular Medicine, University of California San Diego, La Jolla, California 92093, USA.
Smriti VariyarDepartment of Cell & Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA.
SungWoo ParkDepartment of Cell & Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA.
Alessandro E CirulliDepartment of Cellular & Molecular Medicine, University of California San Diego, La Jolla, California 92093, USA.
Karen OegemaDepartment of Cell & Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA.
Kevin D CorbettDepartment of Cellular & Molecular Medicine, University of California San Diego, La Jolla, California 92093, USA.
Arshad DesaiDepartment of Cell & Developmental Biology, School of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA.ORCID 0000-0002-5410-1830

Funding

Kinetochore Specification and FunctionR01GM074215 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DESAI, ARSHAD · 2005 to 2025
$8.2M
Analysis of Centrosome DynamicsR01GM074207 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OEGEMA, KAREN F · 2006 to 2025
$6.6M
Molecular mechanisms of nucleic acid recognition and maintenance in meiosis and innate immunityR35GM144121 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Kevin Daniel Corbett · 2022 to 2026
$2.7M
NIGMS NIH HHS R01 GM074207NIGMS NIH HHS R01 GM074215NIGMS NIH HHS R35 GM144121
6 · The paper itself

Abstract

Accurate chromosome segregation requires dynamic kinetochore-microtubule attachments that, under the regulation of Aurora family kinases, biorient and align replicated chromosomes. In

Identifiers

PMID41279439
PMCPMC12636411

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.