Evidence map›Paper›PMID 41279450›Full record

ArticlebioRxiv : the preprint server for biology2025

A microfluidics-based platform enables discovery of gametogenic rejuvenation factors in

Silvan Spiri, Tina Lynn Sing, Nhi Phung, Jay S Goodman, Elçin Ünal, Gloria Ann Brar

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Silvan SpiriDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.ORCID 0000-0002-7124-3056
Tina Lynn SingDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.ORCID 0000-0002-2166-969X
Nhi PhungDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.
Jay S GoodmanWhitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.ORCID 0000-0002-4788-3918
Elçin ÜnalDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.ORCID 0000-0002-6768-609X
Gloria Ann BrarDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.ORCID 0000-0002-8560-9581

Funding

Illuminating the gene regulatory strategies underlying yeast meiosis and beyondR35GM134886 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Gloria Ann Brar · 2020 to 2026
$3.1M
Defining the programmed proteome rejuvenation underlying gametogenesisR01AG071869 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI BRAR, GLORIA ANN, JOVANOVIC, MARKO · 2021 to 2025
$2.9M
Elucidating Cellular Aging and Quality Control Pathways through Meiotic DifferentiationR01AG071801 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI UNAL, ELCIN · 2021 to 2025
$1.9M
NIA NIH HHS R01 AG071801NIA NIH HHS R01 AG071869NIGMS NIH HHS R35 GM134886
6 · The paper itself

Abstract

During mitotic growth,

Indexed as

autophagycellular rejuvenationgametogenesismeiosismicrofluidicsreplicative lifespanSaccharomyces cerevisiae

Identifiers

PMID41279450
PMCPMC12632322

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.