Evidence mapPaperPMID 41279485Full record

ArticlebioRxiv : the preprint server for biology2025

A chemogenetic ligand-receptor pair for voltage-gated sodium channel subtype-selective inhibition.

Elizabeth R Park, Nicholas Denomme, Holly S Hajare, J Du Bois

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elizabeth R ParkDepartment of Chemistry, Stanford University, Stanford, CA 94305.ORCID 0000-0001-9974-3899
Nicholas DenommeNancy Pritzker Laboratory, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305.ORCID 0000-0002-7631-0385
Holly S HajareDepartment of Chemistry, Stanford University, Stanford, CA 94305.ORCID 0009-0002-2682-4940
J Du BoisDepartment of Chemistry, Stanford University, Stanford, CA 94305.ORCID 0000-0001-7847-1548

Funding

NIGMS NIH HHS R01 GM117263NIGMS NIH HHS T32 GM120007
6 · The paper itself

Abstract

Neuronal excitability relies on the tightly regulated expression and discrete subcellular localization of voltage-gated sodium channels (Na

Identifiers

PMID41279485
PMCPMC12637636

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.