Evidence map›Paper›PMID 41279531›Full record

ArticlebioRxiv : the preprint server for biology2025

A spatial transcriptomic atlas of autism-associated genes identifies convergence in the developing human thalamus.

Alexander Aivazidis, Fani Memi, Koen Rademaker, Mahmoud Koko, Kenny Roberts, Andrew Trinh, Robert Petryszak, Vitalii Kleshchevnikov, Liz Tuck, Steven Lisgo and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alexander AivazidisWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Fani MemiWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Koen RademakerWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Mahmoud KokoWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Kenny RobertsWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.ORCID 0000-0001-6155-0821
Andrew TrinhWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Robert PetryszakWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Vitalii KleshchevnikovWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Liz TuckWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Steven LisgoHuman Developmental Biology Resource, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Tong LiWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Stanislaw MakarchukWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Martin PreteWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Tomasz J NowakowskiDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Hilary C MartinWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
Omer Ali BayraktarWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.ORCID 0000-0001-6055-277X

Funding

Assessing Genomic, Regulatory and Transcriptional Variation at Single Nuclei Resolution in the Brains of Individuals with Autism Spectrum DisorderR01MH125516 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ARNOLD KRIEGSTEIN, Tomasz Nowakowski · 2021 to 2026
$3.8M
Neurodevelopmental defects of the thalamocortical pathway as a convergent feature of psychiatric disordersR01MH128364 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Tomasz Nowakowski, JOHN L. R. RUBENSTEIN · 2023 to 2026
$3.0M
Developmental Timing During Cortical DevelopmentR01NS123263 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Tomasz Nowakowski · 2022 to 2026
$2.1M
NIMH NIH HHS R01 MH125516NIMH NIH HHS R01 MH128364NINDS NIH HHS R01 NS123263Wellcome Trust
6 · The paper itself

Abstract

Autism is a highly heritable neurodevelopmental condition that manifests across a wide phenotypic spectrum. Rare and

Identifiers

PMID41279531
PMCPMC12637553

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.