Evidence map›Paper›PMID 41279800›Full record

ArticlebioRxiv : the preprint server for biology2025

Correlated Gene Copy Number Changes in a Seminal Fluid Protein Network in

J A Carlisle, B K McCormick, L Verbakel, A C von Philipsborn, M F Wolfner, A G Clark

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

J A CarlisleDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853.ORCID 0000-0001-5381-8672
B K McCormickDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853.ORCID 0000-0002-4041-4852
L VerbakelDepartment of Neuroscience and Movement Science, Medicine Section, University of Fribourg, Switzerland.ORCID 0000-0003-0490-8406
A C von PhilipsbornDepartment of Neuroscience and Movement Science, Medicine Section, University of Fribourg, Switzerland.ORCID 0000-0002-7921-8744
M F WolfnerDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853.ORCID 0000-0003-2701-9505
A G ClarkDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853.

Funding

TAKASHIMA DIVERSITY SUPPLEMENT TO: REGULATION OF GAMETE USE AND NEURAL PATHWAYS IN REPRODUCTIONR01HD059060 · NICHD · CORNELL UNIVERSITY · PI ANDREW G CLARK, Mariana Federica Wolfner · 2009 to 2026
$5.8M
Actions of Seminal Proteins in Mated Drosophila FemalesR37HD038921 · NICHD · CORNELL UNIVERSITY · PI Mariana Federica Wolfner · 2020 to 2026
$2.7M
Male x Female Protein Interactions Mediating Reproductive Success in the Drosophila Mating PlugF32HD111231 · NICHD · CORNELL UNIVERSITY · PI Jolie Anna Carlisle · 2023 to 2026
$224k
NICHD NIH HHS F32 HD111231NICHD NIH HHS R01 HD059060NICHD NIH HHS R37 HD038921
6 · The paper itself

Abstract

Reproductive proteins often diverge rapidly between species, yet network function must be maintained. Shared selective pressures on network members and compensatory changes between members can drive their parallel evolutionary trajectories. Indeed, correlated evolutionary rates of amino acid sequence change have been observed for interacting reproductive proteins. But whether gene copy number changes also correlate has not been widely studied. Here, we investigated copy number variation (CNV) of genes in the

Indexed as

CoevolutionCopy Number VariationDrosophilagene duplicationgene lossgene networkSeminal Fluid Proteins

Identifiers

PMID41279800
PMCPMC12636338

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.