Evidence map›Paper›PMID 41279810›Full record

ArticlebioRxiv : the preprint server for biology2025

Discovery of a pre-vein progenitor that requires VEGF/ERK inhibition to complete vein differentiation.

Lay Teng Ang, Sherry Li Zheng, Kevin J Liu, Anastasiia Masaltseva, June Winters, Isabel von Creytz, Sawan K Jha, Qingqing Yin, Crystal Qian, Xiaochen Xiong and 22 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Lay Teng AngInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-6783-4662
Sherry Li ZhengInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Kevin J LiuInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Anastasiia MasaltsevaInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
June WintersDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Isabel von CreytzCenter for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.
Sawan K JhaDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Qingqing YinInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Crystal QianInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Xiaochen XiongInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Amir DailamyInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Ellie XiInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Juan C AlcocerDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Daniel W SorensenDepartment of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA.
Richard SheSchool of Biological Sciences, Nanyang Technological University, Singapore.
Karina SmolyarWhitehead Institute for Biomedical Research, Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.
Dorota SzumskaInstitute of Developmental and Regenerative Medicine, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Svanhild NornesInstitute of Developmental and Regenerative Medicine, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Renata M MartinInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Benjamin J LeschInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Nicole K RestrepoDepartment of Pathology and Cell Biology, University of South Florida, Tampa, Florida, USA.
Wenfei SunDivision of Endocrinology, Department of Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0001-5762-6010
Jonathan S WeissmanWhitehead Institute for Biomedical Research, Department of Biology, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.
Heiko LickertInstitute of Diabetes and Regeneration Research, Helmholtz Center Munich, Neuherberg, Germany.
Matthew H PorteusInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-3850-4648
Mark A Skylar-ScottDepartment of Bioengineering, Basic Science and Engineering Initiative, Children's Heart Center, Chan Zuckerberg Biohub, Stanford University, Stanford, CA, USA.
Christian MosimannDepartment of Pediatrics, Section of Developmental Biology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-0749-2576
Saulius SumanasDepartment of Pathology and Cell Biology, University of South Florida, Tampa, Florida, USA.
Sarah De ValInstitute of Developmental and Regenerative Medicine, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-2566-2348
Joseph B PrescottCenter for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.
Kristy Red-HorseInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.
Kyle M LohInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University, Stanford, CA, USA.ORCID 0000-0002-8042-0149

Funding

Stanford Islet Research CoreP30DK116074 · NIDDK · STANFORD UNIVERSITY · PI Seung K Kim · 2017 to 2026
$19.5M
Scientific Core: Perturb-seq library generation, sequencing, and data analysisP01HL180323 · NHLBI · STANFORD UNIVERSITY · PI JESSE M ENGREITZ · 2025 to 2026
$7.1M
Mechanotransduction and transcriptional regulation during artery developmentR01HL128503 · NHLBI · STANFORD UNIVERSITY · PI Mary Red-Horse · 2015 to 2026
$5.8M
Novel mechanisms of vasculogenesisR01HL153005 · NHLBI · UNIVERSITY OF SOUTH FLORIDA · PI SUMANAS, SAULIUS · 2021 to 2024
$2.0M
Graduate Training in Stem Cell Biology and Regenerative MedicineT32GM119995 · NIGMS · STANFORD UNIVERSITY · PI WEISSMAN, IRVING L. · 2017 to 2021
$2.0M
Developing approaches for universal organ transplantationDP5OD024558 · OD · STANFORD UNIVERSITY · PI LOH, KYLE M · 2017 to 2021
$2.0M
Decoding the transcriptional mechanisms of pericardium formationR01HL168097 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Christian Mosimann · 2024 to 2026
$1.7M
NHLBI NIH HHS P01 HL180323NHLBI NIH HHS R01 HL128503NHLBI NIH HHS R01 HL153005NHLBI NIH HHS R01 HL168097NIDDK NIH HHS P30 DK116074NIGMS NIH HHS T32 GM119995NIH HHS DP5 OD024558
6 · The paper itself

Abstract

Despite substantial insight into mechanisms underlying arterial blood vessel development, multiple aspects of vein development remain elusive, including vein-determining extracellular signals and cell-fate trajectories

Identifiers

PMID41279810
PMCPMC12632389

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.