Evidence map›Paper›PMID 41280222›Full record

ArticleRSC advances2025

Enhancement of mechanical, corrosion, and biocompatibility properties of zinc alloys through magnesium and neodymium alloying for bone implant applications.

Minghan Li, Zhaobo Zhu, Long Zhang, Shaoyu Hu, Jiayi Li, Suiou Li, Xiaohua Jiang, Baoxin Peng, Song Hao

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Minghan LiSpine Surgery Baiyun District People's Hospital of Guangzhou Guangzhou Guangdong China.
Zhaobo ZhuDepartment of Pediatric Orthopedic, Center for Orthopedic Surgery, The Third Affiliated Hospital of Southern Medical University Guangzhou 510515 China.
Long ZhangDepartment of Orthopaedic Surgery, Guangzhou Key Laboratory of Spine Disease Prevention and Treatment, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University Guangzhou 511495 China.
Shaoyu HuDepartment of Spine Orthopedics, Zhuhai People's Hospital The Affiliated Hospital of Beijing Institute of Technology, Zhuhai Clinical Medical College of Jinan University Zhuhai 519000 China haosong527@126.com.
Jiayi LiDepartment of Spine Orthopedics, Zhuhai People's Hospital The Affiliated Hospital of Beijing Institute of Technology, Zhuhai Clinical Medical College of Jinan University Zhuhai 519000 China haosong527@126.com.
Suiou LiSpine Surgery Baiyun District People's Hospital of Guangzhou Guangzhou Guangdong China.
Xiaohua JiangSpine Surgery Baiyun District People's Hospital of Guangzhou Guangzhou Guangdong China.
Baoxin PengThe State Key Laboratory of Respiratory Disease, Department of Otolaryngology, Head and Neck Surgery, Laboratory of ENT-HNS Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University Guangzhou 510120 China bxin_peng@163.com.
Song HaoDepartment of Spine Orthopedics, Zhuhai People's Hospital The Affiliated Hospital of Beijing Institute of Technology, Zhuhai Clinical Medical College of Jinan University Zhuhai 519000 China haosong527@126.com.ORCID https://orcid.org/0009-0003-5233-829X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc (Zn) alloys, though beneficial for biodegradable applications due to their controlled degradation, biocompatibility, and potential to aid in bone healing, often suffer from inadequate mechanical properties. To enhance their performance, this study investigates the incorporation of magnesium (Mg) and neodymium (Nd) as alloying elements and applies hot extrusion to produce Zn-based alloys with superior mechanical and biological characteristics suitable for moderate load-bearing orthopedic uses. The resulting Zn-0.1Mg-1Nd alloy exhibits a fine-grained structure with an average grain size of 1.36 µm, which enhances its tensile strength from 71 MPa for pure Zn to 381 MPa for the alloy, alongside a notable increase in elongation from 10.7% to 17.7%. These improvements fulfill the mechanical requirements for biodegradable bone-fixation devices. Corrosion tests, including electrochemical and immersion assessments in simulated body fluid (SBF), demonstrate the alloy's enhanced degradation resistance, with the lowest corrosion rate recorded at 0.094 mm year

Identifiers

PMID41280222
PMCPMC12631173

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.