Evidence map›Paper›PMID 41280269›Full record

ArticleClinical case reports2025

Diffuse Large B-Cell Lymphoma Combined With Paroxysmal Nocturnal Hemoglobinuria: A Rare Case Report.

Zhen Zhen Liu, Da Lin Di, An Hua Feng, Jie Yu, Hai Ying Wang, Lili Qin

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhen Zhen LiuDepartment of Hematology Affiliated Hospital of Shandong Second Medical University Weifang China.ORCID https://orcid.org/0009-0005-3682-6458
Da Lin DiDepartment of Immunology Shandong Second Medical University Weifang China.
An Hua FengDepartment of Hematology Affiliated Hospital of Shandong Second Medical University Weifang China.
Jie YuDepartment of Hematology Affiliated Hospital of Shandong Second Medical University Weifang China.
Hai Ying WangDepartment of Hematology Affiliated Hospital of Shandong Second Medical University Weifang China.
Lili QinDepartment of Hematology Affiliated Hospital of Shandong Second Medical University Weifang China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse large B-cell lymphoma (DLBCL) is a common hematological malignancy, and some patients may present with autoimmune hemolytic anemia (AIHA). However, the coexistence of DLBCL and paroxysmal nocturnal hemoglobinuria (PNH) is rare. PNH patients may develop myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), but lymphomas are rarely seen. Here, we focus on a 46-year-old female patient afflicted with PNH for 3 years before being diagnosed with DLBCL. Different from DLBCL accompanied by AIHA, this case did not benefit from the R-CHOP regimen. This case demonstrates that PNH can coexist with malignant lymphoma, which is a rare finding. It also enhances our understanding of the clinical management of DLBCL coexisting with PNH.

Indexed as

diffuse large B‐cell lymphomahemolysisparoxysmal nocturnal hemoglobinuriavenous thrombosis

Identifiers

PMID41280269
PMCPMC12634037

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.