Evidence map›Paper›PMID 41280326›Full record

ReviewJRSM cardiovascular disease

Clinical phenotypes of atrial fibrillation: A review of machine learning applications in personalized treatment.

Richard J Woodman, Huah Shin Ng, Arduino A Mangoni

Abstract readReview
In one paragraph

Review in JRSM cardiovascular disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Richard J WoodmanFlinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.ORCID https://orcid.org/0000-0002-4094-1222
Huah Shin NgFlinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.ORCID https://orcid.org/0000-0001-8381-5253
Arduino A MangoniDiscipline of Pharmacology, College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.ORCID https://orcid.org/0000-0001-8699-1412

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is a clinically heterogeneous syndrome where traditional 'one-size-fits-all' management strategies are often suboptimal. This review synthesizes the contemporary application of machine learning (ML) and deep learning (DL) in identifying distinct clinical AF phenotypes to advance personalized treatment. We provide a comprehensive overview of over a dozen key phenotyping studies, highlighting the consistent identification of core patient subgroups across diverse international cohorts, including low-risk/younger, atherosclerotic/high-cardiovascular-risk, and elderly/multi-morbid phenotypes. A detailed comparative summary of these studies, their methodologies, and their prognostic findings is presented. Our review also illustrates how these data-driven phenotypes are being leveraged to guide personalized therapy. We detail specific ML applications in optimizing medication selection and dosing, particularly for anticoagulants, and in advancing catheter ablation strategies. Key innovations in ablation include AI-guided anatomical mapping,

Indexed as

artificial intelligenceAtrial fibrillationcatheter ablationcluster analysismachine learningpersonalized medicinephenotypingprecision medicinereviewrisk stratificationstroke

Identifiers

PMID41280326
PMCPMC12639216

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.