Evidence map›Paper›PMID 41280564›Full record

ArticleAmerican journal of nuclear medicine and molecular imaging2025

Visualizing T-cell activation: PET imaging of CXCL9 as a window into the tumor immune response.

Jimmy S Patel, Runhong Li, Steven H Liang

Abstract readEditorial
In one paragraph

Article in American journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jimmy S PatelDepartment of Radiation Oncology, Winship Cancer Institute of Emory University Atlanta, Georgia 30322, The United States.
Runhong LiDepartment of Radiology and Imaging Sciences, Emory University 1364 Clifton Road, Atlanta, Georgia 30322, The United States.
Steven H LiangDepartment of Radiology and Imaging Sciences, Emory University 1364 Clifton Road, Atlanta, Georgia 30322, The United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T-cell activation within the tumor microenvironment is a key determinant of response to immunotherapy, yet current biomarkers fail to capture its spatial and temporal dynamics. Traditional assays such as PD-L1 immunohistochemistry, tumor mutational analysis, and circulating cytokine profiling offer static or systemic snapshots that inadequately reflect localized immune engagement. Positron emission tomography (PET) provides a unique opportunity to visualize these processes

Indexed as

CXCL9microenvironmentPETtumor

Identifiers

PMID41280564
PMCPMC12629901

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.