Evidence map›Paper›PMID 41280799›Full record

ArticleACS omega2025

Pre- and Post-treatment Impact of Antioxidants on Astrocytic Reactive Oxygen SpeciesAn Undergraduate Classroom Research Project.

Haley Yost, Kaejaren C N Caldwell, Jooyoung Cho, Lindsay E Cormier, Tanea T Reed

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haley YostEastern Kentucky University, 521 Lancaster Ave, Richmond, Kentucky 40475, United States.
Kaejaren C N CaldwellUniversity of Cincinnati, 312 College Dr, Cincinnati, Ohio 45221, United States.
Jooyoung ChoEastern Kentucky University, 521 Lancaster Ave, Richmond, Kentucky 40475, United States.
Lindsay E CormierEastern Kentucky University, 521 Lancaster Ave, Richmond, Kentucky 40475, United States.
Tanea T ReedEastern Kentucky University, 521 Lancaster Ave, Richmond, Kentucky 40475, United States.ORCID https://orcid.org/0000-0003-2642-3100

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
NIGMS NIH HHS P20 GM103436
6 · The paper itself

Abstract

Undergraduate research is a method to enhance student engagement in science courses as well as expand scientific curiosity. One method in doing so is performing course undergraduate research experiences. This project started as an undergraduate research project and expanded into a six-week in-class honor's research experience. The field of traumatic brain injury (TBI) evokes instant name recognition and interest among undergraduate students based on their previous knowledge of sports and related concussion consequences in the news and on social media platforms. Currently, there is no clear treatment for traumatic brain injury. The rise of TBI-related deaths and debilitation has driven research efforts. Secondary effects of TBI are a current focus for research efforts including the regulation of oxidative stress within mitochondrial pathways. This work aims to investigate antioxidant therapies in preventing oxidative stress, a consequence of traumatic brain injury. Oxidative stress was stimulated by hydrogen peroxide (H

Identifiers

PMID41280799
PMCPMC12631681

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.