Evidence map›Paper›PMID 41280871›Full record

ArticleACS omega2025

Evaluation of the Activity of 4‑Quinolones against Multi-Life Stages of

Yasmin Annunciato, Everton M da Silva, Jéssica E Araújo, Leandro do N Martinez, Sofia Santana, Eyob A Workneh, Luís C S Alvarez, Marcela L Magalhães, Alice Oliveira Andrade, Wallyson de J da Costa and 22 more

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Yasmin AnnunciatoLaboratory of cell biology and biochemistry of parasitic diseases, Biosciences department, Universidade Federal de São Paulo, Rua Silva Jardim, 136 - Vila Matias, Santos, São Paulo 11015-020, Brazil.
Everton M da SilvaDepartment of Chemistry, Universidade Federal de São Carlos, Rodovia Washington Luís, s/n, São Carlos, São Paulo 13565-905, Brazil.
Jéssica E AraújoMalaria Vector Production and Infection Platform (PIVEM)/Entomology Lab, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Leandro do N MartinezBioassay Platform for Malaria and Leishmaniasis, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Sofia SantanaPlasmodium infection and anti-malarial interventions, GIMM - Gulbenkian Institute for Molecular Medicine, Avenida Prof. Egas Moniz, Lisboa 1649-035, Portugal.
Eyob A WorknehPlasmodium infection and anti-malarial interventions, GIMM - Gulbenkian Institute for Molecular Medicine, Avenida Prof. Egas Moniz, Lisboa 1649-035, Portugal.ORCID https://orcid.org/0009-0007-1562-9644
Luís C S AlvarezLaboratory of Tropical Diseases Prof. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas (UNICAMP), Cidade Universitária Zeferino Vaz - Barão Geraldo, Campinas, São Paulo 13083-970, Brazil.
Marcela L MagalhãesLaboratory of Tropical Diseases Prof. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas (UNICAMP), Cidade Universitária Zeferino Vaz - Barão Geraldo, Campinas, São Paulo 13083-970, Brazil.
Alice Oliveira AndradeMalaria Vector Production and Infection Platform (PIVEM)/Entomology Lab, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Wallyson de J da CostaBioassay Platform for Malaria and Leishmaniasis, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Guilherme CampolinaLaboratory of Malaria Research, Microbiology and Imunology Departament, Universidade Federal de São Paulo, Rua Botucatu, 862 - Vila Clementino, São Paulo, São Paulo 04023-062, Brazil.
Matheus Nascimento SantanaLaboratory of Malaria Research, Microbiology and Imunology Departament, Universidade Federal de São Paulo, Rua Botucatu, 862 - Vila Clementino, São Paulo, São Paulo 04023-062, Brazil.
Camila S BarbosaLaboratory of Malaria Research, Microbiology and Imunology Departament, Universidade Federal de São Paulo, Rua Botucatu, 862 - Vila Clementino, São Paulo, São Paulo 04023-062, Brazil.
Erica P M L PeresLaboratory of cell biology and biochemistry of parasitic diseases, Biosciences department, Universidade Federal de São Paulo, Rua Silva Jardim, 136 - Vila Matias, Santos, São Paulo 11015-020, Brazil.
Caio S MouraLaboratory of cell biology and biochemistry of parasitic diseases, Biosciences department, Universidade Federal de São Paulo, Rua Silva Jardim, 136 - Vila Matias, Santos, São Paulo 11015-020, Brazil.
Najara A C Dos SantosMalaria Vector Production and Infection Platform (PIVEM)/Entomology Lab, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Alessandra da S BastosMalaria Vector Production and Infection Platform (PIVEM)/Entomology Lab, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Roberto Rudge de M BarrosLaboratory of Malaria Research, Microbiology and Imunology Departament, Universidade Federal de São Paulo, Rua Botucatu, 862 - Vila Clementino, São Paulo, São Paulo 04023-062, Brazil.
Marcos L GazariniLaboratory of cell biology and biochemistry of parasitic diseases, Biosciences department, Universidade Federal de São Paulo, Rua Silva Jardim, 136 - Vila Matias, Santos, São Paulo 11015-020, Brazil.
Jansen Fernandes MedeirosMalaria Vector Production and Infection Platform (PIVEM)/Entomology Lab, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Carolina B G TelesBioassay Platform for Malaria and Leishmaniasis, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Fabio T M CostaLaboratory of Tropical Diseases Prof. Luiz Jacintho da Silva, Department of Genetics, Evolution, Microbiology and Immunology, University of Campinas (UNICAMP), Cidade Universitária Zeferino Vaz - Barão Geraldo, Campinas, São Paulo 13083-970, Brazil.ORCID https://orcid.org/0000-0001-9969-7300
Ana C AlvesGlobal Health and Tropical Medicine, Associate Laboratory in Translation and Innovation Towards Global Health, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 100, Lisbon 1349-008, Portugal.
Dhelio B PereiraMedicina Tropical e Doenças Infecciosas Department, Centro de Pesquisa em Medicina Tropical de Rondônia - CEPEM, Av. Guaporé - Lagoa, 415 303, Porto Velho, Rondônia 76.812-329, Brazil.
João PintoGlobal Health and Tropical Medicine, Associate Laboratory in Translation and Innovation Towards Global Health, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 100, Lisbon 1349-008, Portugal.
Pedro V L CravoGlobal Health and Tropical Medicine, Associate Laboratory in Translation and Innovation Towards Global Health, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 100, Lisbon 1349-008, Portugal.
Rafael Victorio Carvalho GuidoSão Carlos Institute of Physics, Universidade de São Paulo, Avenida Trab. São Carlense, 400 - Parque Arnold Schimidt, São Carlos, São Paulo 13566-590, Brazil.
Miguel PrudêncioPlasmodium infection and anti-malarial interventions, GIMM - Gulbenkian Institute for Molecular Medicine, Avenida Prof. Egas Moniz, Lisboa 1649-035, Portugal.
Maisa da S AraujoMalaria Vector Production and Infection Platform (PIVEM)/Entomology Lab, Fundação Oswaldo Cruz, R. da Beira, 7671 - Lagoa, Porto Velho, Rondônia 76812-245, Brazil.
Arlene G CorrêaDepartment of Chemistry, Universidade Federal de São Carlos, Rodovia Washington Luís, s/n, São Carlos, São Paulo 13565-905, Brazil.ORCID https://orcid.org/0000-0003-4247-2228
Gustavo C CassianoGlobal Health and Tropical Medicine, Associate Laboratory in Translation and Innovation Towards Global Health, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Rua da Junqueira, 100, Lisbon 1349-008, Portugal.
Anna C C AguiarLaboratory of cell biology and biochemistry of parasitic diseases, Biosciences department, Universidade Federal de São Paulo, Rua Silva Jardim, 136 - Vila Matias, Santos, São Paulo 11015-020, Brazil.ORCID https://orcid.org/0000-0003-0139-8279

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is a critical global health problem, with high mortality and morbidity rates, which ultimately hinder socioeconomic development in endemic areas. The evolution of drug resistance in malaria parasites, particularly in the case of

Identifiers

PMID41280871
PMCPMC12631437

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.