Evidence mapPaperPMID 41280964Full record

ReviewCureus2025

Antioxidant Nutrients and Diabetes and Its Complications: A Narrative Review on the Roles of Vitamin E, Vitamin C, and Selenium.

Mahesh Kumar Mummadi, Shankar Sapavat, Indiramma Ettey, Tejaswini Appala, Jag Jeevan Babu Geddam

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahesh Kumar MummadiClinical Epidemiology, Indian Council of Medical Research (ICMR) National Institute of Nutrition, Hyderabad, IND.
Shankar SapavatPublic Health Nutrition, Indian Council of Medical Research (ICMR) National Institute of Nutrition, Hyderabad, IND.
Indiramma EtteyClinical Epidemiology, Indian Council of Medical Research (ICMR) National Institute of Nutrition, Hyderabad, IND.
Tejaswini AppalaClinical Epidemiology, Indian Council of Medical Research (ICMR) National Institute of Nutrition, Hyderabad, IND.
Jag Jeevan Babu GeddamClinical Epidemiology, Indian Council of Medical Research (ICMR) National Institute of Nutrition, Hyderabad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This narrative review summarizes the evidence on vitamin E, vitamin C, and selenium in preventing or mitigating diabetes, diabetic neuropathy, and associated complications. A comprehensive literature search was conducted in MEDLINE for English language studies from January 2000 to April 2025 using terms such as "vitamin E," "selenium", "antioxidant", "diabetes", and "neuropathy". Randomized clinical trials were included without grading restrictions. Antioxidants such as vitamin E, selenium, and vitamin C show potential in reducing oxidative stress, improving glycemic control, and alleviating diabetic complications. However, findings are inconsistent, emphasizing the need for personalized approaches and further trials to clarify their therapeutic roles. A balanced diet rich in antioxidant-containing foods continues to be recommended to support metabolic health and reduce the risk of diabetes-related complications.

Indexed as

antioxidantdiabetic neuropathyoxidative stressseleniumvitamin e

Identifiers

PMID41280964
PMCPMC12633781

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.