Evidence map›Paper›PMID 41281137›Full record

ReviewCureus2025

Revolutionizing Allergy Care: Sublingual Immunotherapy for House Dust Mite Allergy.

Taha A Qureshi, Sitesh Roy, Gautam Modi, Neeraj Gupta, Gayatri Pandit, Devesh K Joshi, Monil Gala

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Taha A QureshiAllergy, Jawahar Lal Nehru Memorial Hospital, Srinagar, IND.
Sitesh RoyAllergy, Dr. Roy Health Solutions Clinic, Mumbai, IND.
Gautam ModiAllergy, Modi Allergy Clinic, Patna, IND.
Neeraj GuptaPediatrics and Allergy, Sir Ganga Ram Hospital, New Delhi, IND.
Gayatri PanditAllergy, Samarth ENT and Allergy Centre, Bangalore, IND.
Devesh K JoshiMedical Affairs, Dr. Reddy's Laboratories Ltd., Hyderabad, IND.
Monil GalaMedical Affairs, Dr. Reddy's Laboratories Ltd., Hyderabad, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

House dust mite (HDM) allergies affect a significant portion of the global population. A considerable number of people in India suffer from allergic rhinitis (AR), and many individuals with AR are affected by HDM allergies. The management of allergic conditions, such as AR and allergic asthma (AA), has predominantly depended on drugs providing symptomatic relief and avoidance measures. These approaches do not include disease-modifying drugs and have limitations, including incomplete relief, slow onset of action, lack or drop-off in efficacy with continued use, and frequent exacerbations. With multiple species of HDM in India and high rates of sensitization among patients with nasobronchial allergy, symptomatic management is inadequate. Allergen immunotherapy (AIT), including sublingual immunotherapy (SLIT), represents the only disease-modifying treatment for allergic conditions. Unlike subcutaneous immunotherapy (SCIT), SLIT has the advantages of being non-invasive, allowing at-home administration, and having a lower potential for anaphylactic reactions. This review highlights the need for SLIT and explores the mechanism and clinical benefits of this novel immunotherapy.

Indexed as

allergic rhinitisasthmadermatophagoidesdust mitessublingual immunotherapy

Identifiers

PMID41281137
PMCPMC12630047

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.