Evidence map›Paper›PMID 41281544›Full record

ArticleJournal of toxicology2025

Evaluation of the Nephroprotective Activity of Crude Extract Root of

Asrat Tadelle Ewunetie, Banchamlak Teferi, Melkamu Siferih, Yadelew Yimer, Tiget Ayelgn Mengstie, Tewodros Shibabaw Molla

Abstract read
In one paragraph

Article in Journal of toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Asrat Tadelle EwunetieDepartment of Biomedical Science, College of Health Sciences, Debre Birhan University, Debre Birhan, Ethiopia.
Banchamlak TeferiDepartment of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Melkamu SiferihDepartment of Obstetrics and Gynecology, School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
Yadelew YimerDepartment of Biochemistry, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Tiget Ayelgn MengstieDepartment of Biochemistry, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Tewodros Shibabaw MollaDepartment of Biochemistry, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.ORCID https://orcid.org/0000-0002-9155-4898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute kidney injury represents a spectrum of diseases and is one of the most common threats to global public health. Gentamicin is the most common nephrotoxic antibiotic drug. Consequently, there is an urgent need to identify effective and safe therapeutic options from medicinal plants. Therefore, the purpose of this in vivo study is to evaluate the nephroprotective effects of the root of Methods: A total of 30 mice were divided into five groups of six mice each. It comprised a normal control group (Group I) that received distilled water orally, Group II (100 mg/kg gentamicin-induced) without any intervention, and Group III-V that were experimental groups induced with 100 mg/kg gentamicin and treated with extracts of Result: Conclusion: This study explained that the extracts of

Indexed as

gentamicinnephroprotectivenephrotoxicityRumex abyssinicus

Identifiers

PMID41281544
PMCPMC12638155

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.