Evidence map›Paper›PMID 41281849›Full record

ArticleJournal of orthopaedic case reports2025

Relation of Serum Vitamin-D Level with Serum Interleukin-6 and Interleukin-10 in Patients with Primary Osteoarthritis of Knee.

Ankit Kumar Tetarwal, Rajni Ranjan, Rakesh Kumar, Varun Dhattarwal, Swaminathan Ramasubramanian, Madhan Jeyaraman

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In one paragraph

Article in Journal of orthopaedic case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ankit Kumar TetarwalDepartment of Orthopaedics, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India.
Rajni RanjanDepartment of Orthopaedics, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India.
Rakesh KumarDepartment of Orthopaedics, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India.
Varun DhattarwalDepartment of Orthopaedics, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India.
Swaminathan RamasubramanianDepartment of Regenerative Medicine, Agathisha Institute of Stemcell and Regenerative Medicine (AISRM), Chennai, Tamil Nadu, India.
Madhan JeyaramanDepartment of Regenerative Medicine, Agathisha Institute of Stemcell and Regenerative Medicine (AISRM), Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Osteoarthritis (OA) of the knee is a prevalent degenerative condition influenced by inflammatory processes. Vitamin D possesses immunomodulatory properties that could potentially impact cytokine expression, notably interleukin (IL)-6 and -10, in osteoarthritic pathology. This study investigates the correlation between serum vitamin D (25-hydroxyvitamin D Material And Methods: This cross-sectional observational study included 80 patients aged above 45 years diagnosed with primary knee OA confirmed radiologically (Kellgren-Lawrence grading). Participants underwent serum analysis for vitamin D Results: Mean serum vitamin D Conclusions: A significant inverse association between serum vitamin D

Indexed as

inflammationinterleukin-10interleukin-6knee jointOsteoarthritisvitamin D

Identifiers

PMID41281849
PMCPMC12636808

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.