ArticleVirusdisease2025
Assessing COVID-19 IgG levels among vaccinated and non-vaccinated individuals in Mthatha - South africa: A case-control approach.
Article in Virusdisease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Faced with the emergence of new COVID-19 variants, vaccine hesitancy remains a major challenge in the global fight against the pandemic, particularly in rural areas. Understanding the immune response to vaccination is crucial for dispelling doubts and building public trust. By providing tangible evidence of vaccine effectiveness, this approach could not only alleviate skepticism but also contribute to preventing future epidemics. To evaluate and compare salivary SARS-CoV-2 IgG antibody levels between vaccinated and unvaccinated individuals in Mthatha, South Africa. A case-control study involved 183 participants aged 18 years and above, comprising 91 vaccinated and 92 unvaccinated individuals in Mthatha, South Africa. Saliva samples were collected and analyzed using Bio-Plex Pro Human IgG SARS-CoV-2 Assay to detect SARS-CoV-2 IgG antibodies. Data were processed using STATA/SE version 18.0. The results of this study demonstrate that participants vaccinated against COVID-19 exhibit significantly ( Supplementary Information: The online version contains supplementary material available at 10.1007/s13337-025-00942-w.
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