Evidence map›Paper›PMID 41282019›Full record

ArticleFrontiers in medicine2025

Effectiveness of Five-Element Regulatory Therapy for post-COVID syndrome: a retrospective cohort study.

Ning Ding, Yunqiao Zhou, Haolin Zhang, Xiyan Xin, Yang Ye, Dong Li

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ning DingDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, China.
Yunqiao ZhouDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Haolin ZhangDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, China.
Xiyan XinDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, China.
Yang YeDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, China.
Dong LiDepartment of Traditional Chinese Medicine, Peking University Third Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Post-COVID syndrome is characterized by persistent, unexplained symptoms including chronic cough, palpitations, insomnia, and fatigue that develop following SARS-CoV-2 infection without identifiable causes. Current treatments show limited efficacy, requiring alternative options. This study aims to observe the effectiveness of Five-Element Regulation Therapy (FERT), a Traditional Chinese medicine (TCM) intervention, in managing post-COVID syndrome. Methods: A retrospective cohort study was conducted using clinical records of 127 post-COVID syndrome patients from the TCM outpatient department of Peking University Third Hospital. The participants were divided into two groups: 81 cases receiving FERT treatment were assigned to the exposure group, while 46 cases undergoing conventional TCM therapy served as the control group. The treatment duration was 2 weeks for both groups, followed by immediate follow-up. The outcomes included the clinical cure rate and clinical response rate at 2 weeks after the treatment initiation. Results: The FERT group demonstrated superior clinical outcomes, achieving a 61.7% cure rate and 88.9% response rate, significantly higher than the control group's 21.7% ( Conclusion: This study provides preliminary evidence that FERT may be superior to conventional TCM therapy in managing post-COVID syndrome. Results should be interpreted with heightened caution due to the study's inherent limitations.

Indexed as

corona virus disease 2019Five-Element Regulation Therapypost-COVID syndromeretrospective studyTraditional Chinese Medicine

Identifiers

PMID41282019
PMCPMC12631303

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.