Evidence map›Paper›PMID 41282102›Full record

ArticleResearch square2025

IND-Enabling Preclinical Studies of [11C]COU, a Trapped Metabolite PET Radiotracer for Monoamine Oxidase-B.

Madison Frazier, Tanpreet Kaur, Jenelle Stauff, Wade P Winton, Bradford D Henderson, Alexandra S Dumond, Xia Shao, David M Raffel, Kirk A Frey, Michael R Kilbourn and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Madison FrazierUniversity of Michigan.
Tanpreet KaurUniversity of Michigan.
Jenelle StauffUniversity of Michigan.
Wade P WintonUniversity of Michigan.
Bradford D HendersonUniversity of Michigan.
Alexandra S DumondUniversity of Michigan.
Xia ShaoUniversity of Michigan.
David M RaffelUniversity of Michigan.
Kirk A FreyUniversity of Michigan.
Michael R KilbournUniversity of Michigan.
Allen F BrooksUniversity of Michigan.
Peter J H ScottUniversity of Michigan.

Funding

NIA NIH HHS R21 AG073686NINDS NIH HHS R21 NS075553
6 · The paper itself

Abstract

[

Indexed as

DosimetryMAO-BPET imagingPharmacology/ToxicologyPreclinical studySynthesis validation

Identifiers

PMID41282102
PMCPMC12633532

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.