Evidence map›Paper›PMID 41282285›Full record

ArticleFrontiers in endocrinology2025

Association of co-occurrence of gastrointestinal, sleep, and affective symptoms with

ZhiHai Zhang, HongFei Ke, XiaoYan ShangGuan, NengJiang Zhao, Xin Hu, Bo Li, MiaoNa Cai, MeiQi Chen, JiaHao Liu, JieLong Wu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

ZhiHai ZhangCenter of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
HongFei KeCenter of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
XiaoYan ShangGuanThe First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian,, China.
NengJiang ZhaoCenter of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Xin HuCenter of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Bo LiCenter of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
MiaoNa CaiCenter of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
MeiQi ChenGuangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
JiaHao LiuGuangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, China.
JieLong WuCenter of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
ShuYu YangCenter of Integrated Chinese and Western Medicine, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: This single-center cross-sectional study enrolled 969 adults at a Results: In terms of associated symptoms, 35.40% of participants reported gastrointestinal symptoms, 72.65% had sleep disturbances, and 61.09% experienced affective disorders. The prevalence of gastrointestinal symptoms, sleep disturbances, and affective disorders increased significantly with greater infection severity. LCA identified a "Positive Triad" phenotype (60.7% of the cohort), characterized by concurrent gastrointestinal, sleep, and emotional symptoms. Higher infection severity was independently associated with this combined symptom cluster after adjusting for age, sex, and BMI. The effect of Conclusion:

Indexed as

Affective SymptomsGastrointestinal DiseasesHelicobacter InfectionsHelicobacter pyloriSleep Wake DisordersAdultAgedChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceaffectivedisordersextra-gastric manifestationsHelicobacter pylorisleep disturbancestriadic symptom cluster

Identifiers

PMID41282285
PMCPMC12634323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.