Evidence mapPaperPMID 41283188Full record

ReviewJournal of ophthalmology2025

Corneal Biomechanical Changes Induced by Chronic Elevated Intraocular Pressure: Implications for Glaucoma Pathogenesis and Management.

Mengzhen Xie, Zhiyong Huang, Ke Ma, Yingping Deng, Jing Tang

Abstract readReview
In one paragraph

Review in Journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mengzhen XieOphthalmology Department of West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.ORCID https://orcid.org/0000-0002-1967-1029
Zhiyong HuangSichuan University, Chengdu, Sichuan, China.ORCID https://orcid.org/0000-0003-3500-3538
Ke MaOphthalmology Department of West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.ORCID https://orcid.org/0000-0002-5193-428X
Yingping DengOphthalmology Department of West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.ORCID https://orcid.org/0000-0001-7653-658X
Jing TangOphthalmology Department of West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.ORCID https://orcid.org/0000-0003-0720-8616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The significance and contributions of corneal biomechanics in the study of chronic elevated intraocular pressure are multifaceted. Not only does it enhance our understanding of how chronic elevated intraocular pressure affects corneal structure and function, but it also offers new perspectives for the early diagnosis of glaucoma. Analysis of the cornea's biomechanical properties enables earlier identification of high-risk glaucoma patients and potential development of personalized treatment plans, thereby improving treatment outcomes. Moreover, changes in corneal biomechanics can serve as a new metric for assessing glaucoma treatment effectiveness, providing precise clinical feedback. Continued research on the role of corneal biomechanics in chronic elevated intraocular pressure and glaucoma is crucial for improving the diagnosis, treatment, and prognosis. Understanding associations between these biomechanical changes and glaucoma development can elucidate disease mechanisms, enabling more effective treatment strategies and preventive measures. This review explores the latest research developments on corneal biomechanical changes associated with chronic elevated intraocular pressure and their impact on glaucoma management, highlighting the importance of these changes in clinical practice.

Identifiers

PMID41283188
PMCPMC12638173

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.