ArticleClinical oral investigations2025
Impact of lifestyle behaviors on clinical outcomes of steps 1 and 2 of periodontal therapy in stage iii-iv periodontitis: a cohort study.
Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Healthy lifestyle and periodontitis: a multi-omics cross-sectional study in a Chinese cohort.Journal of oral microbiology · 2026Article
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8 authors.
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Abstract
objectiveGiven the inconsistent evidence in the literature, the aim of this prospective cohort study was to evaluate the impact of lifestyle on the clinical response to Steps 1 and 2 of periodontal therapy in patients with severe periodontitis. MATERIALS AND
methodsPatients with untreated stage III/IV periodontitis received non-surgical periodontal therapy and were re-evaluated 3 months later (T1). Based on baseline self-administered questionnaires, four lifestyle factors - physical activity, dietary habits, smoking, and alcohol consumption- were scored as either healthy (1 point) or unhealthy (0 point). An overall healthy lifestyle variable was calculated for each patient by summing the individual scores (ranging from 0 to 4 points), and its impact on clinical outcomes was analyzed. The primary outcome of the study was disease control (≤ 4 residual probing pocket depth (PPD) ≥ 5 mm).
resultsA total of 120 patients were treated. At T1, a statistically significant association was observed between the overall lifestyle score and treatment response (p = 0.029). Specifically, 55.1% of patients with healthy lifestyle behaviors (score 3-4) achieved the primary endpoint, compared to 29.0% and 32.5% of those with partial (score 2) or poor health attentiveness (score 0-1), respectively. Additionally, health-conscious individuals demonstrated better control of gingival inflammation, despite having comparable oral hygiene levels (p < 0.001). In the logistic regression model, attentiveness to one's health (OR 3.39, 95% CI 1.13-9.47, p = 0.020), normal body weight (OR 2.93, 95% CI 1.12-7.70, p = 0.029) and percentage of sites with PPD ≥ 6 mm at baseline (OR 0.90, 95% CI = 0.84-0.97, p = 0.006) were significantly associated with treatment outcome.
conclusionAdherence to positive healthy lifestyle factors contributes to better clinical outcomes following periodontal therapy in patients with stage III/IV periodontitis. CLINICAL RELEVANCE: The adoption of healthy lifestyle behaviors should be considered as part of the overall management strategy for patients with severe periodontitis.
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