ArticleAmerican journal of physiology. Heart and circulatory physiology2026
Normal cardiac lymphatics and their mimics.
Article in American journal of physiology. Heart and circulatory physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The Thoracic Lymphatic Vasculature: Interorgan Strategies to Achieve an Optimal Tissue Function.Comprehensive Physiology · 2026Review
- Active endothelial and neural regulation of valve biology, health, and disease.Frontiers in cardiovascular medicine · 2026Review
- The role of the cardiac lymphatic system in heart failure "reverse remodeling": from developmental signals to druggable targets.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Significant lymphatic structural remodeling and dysfunction have been observed in preclinical models of cardiovascular disease. However, a detailed understanding of the normal structure and distribution of lymphatic vessels (LyVs) in the heart is still lacking. The goal of this study is to define the pattern of LyVs at various cardiac anatomical sites using Prox1-tdTomato lymphatic reporter mice. By light sheet microscopy, we first confirmed the presence of an extensive network of LyVs on the epicardial surface of the ventricles, while minimal signal was detected on the atria. We then evaluated LyV distribution within the heart using cryo- and vibratome sections. To ensure accurate identification of Prox1-tdTomato
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.