ArticleNature communications2025
Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels.
Reem Handklo-Jamal, Tal Keren Raifman, Boris Shalomov, Patrick Hofer, Uri Kahanovitch, Theres Friesacher, Galit Tabak, Vladimir Tsemakhovich, Haritha P Reddy, Orna Chomsky-Hecht and 9 more
Abstract read
In one paragraphArticle in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
19 authors.
Tal Keren RaifmanDepartment of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel.
Uri KahanovitchDepartment of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel.
Galit TabakDepartment of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel.
Vladimir TsemakhovichDepartment of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel.
Orna Chomsky-HechtDepartment of Biochemistry & Molecular Biology, School of Neurobiology, Biochemistry and Biophysics, George S. Weiss Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
Debi Ranjan TripathyDepartment of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel.
Kerstin ZuhlkeMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.
Joel A HirschDepartment of Biochemistry & Molecular Biology, School of Neurobiology, Biochemistry and Biophysics, George S. Weiss Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID http://orcid.org/0000-0001-7544-8668 Anna Stary-WeinzingerDepartment of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Josef-Holaubek-Platz 2, Vienna, Austria. anna.stary@univie.ac.at.ORCID http://orcid.org/0000-0002-9202-0484 Funding
Regulation of Adenylyl Cyclase Signaling PathwaysR35GM145291 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Carmen W. Dessauer · 2022 to 2026
$2.1MAustrian Science Fund (Fonds zur Förderung der Wissenschaftlichen Forschung) W1232Israel Science Foundation (ISF) 1282/18 and 581/22NIGMS NIH HHS R35 GM145291U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35GM145921
6 · The paper itselfAbstract
Indexed as
G Protein-Coupled Inwardly-Rectifying Potassium ChannelsGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsAnimalsHEK293 CellsHumansOocytesProtein BindingSignal TransductionXenopus laevisG Protein-Coupled Inwardly-Rectifying Potassium ChannelsGTP-Binding Protein beta SubunitsGTP-Binding Protein gamma SubunitsKCNJ6 protein, human
Identifiers
PMID41285859
PMCPMC12748987
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390