Evidence map›Paper›PMID 41286124›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Persistent lung and vascular inflammation in mild to moderate COVID-19 survivors detected by ¹⁸F-FDG PET/CT: A quantitative imaging study with implications for cardiovascular risk.

Shipra Verma, Nick S R Lan, Heidi Espedal, Jeremy Ong, Ambuj Roy, Adilah Ahmad, Kamar Ali, Natalie C Ward, Sanjay Patel, Paul M Parizel and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shipra VermaHarry Perkins Institute of Medical Research, Murdoch, WA, Australia.
Nick S R LanHarry Perkins Institute of Medical Research, Murdoch, WA, Australia.
Heidi EspedalWestern Australia National Imaging Facility, University of Western Australia, Perth, WA, Australia.
Jeremy OngDepartment of Nuclear Medicine, Fiona Stanley Hospital, Murdoch, WA, Australia.
Ambuj RoyDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Adilah AhmadHarry Perkins Institute of Medical Research, Murdoch, WA, Australia.
Kamar AliDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.
Natalie C WardDobney Hypertension Centre, Medical School, University of Western Australia, Perth, WA, Australia.
Sanjay PatelHeart Research Institute, University of Sydney, Sydney, NSW, Australia.
Paul M ParizelMedical School, University of Western Australia, Perth, WA, Australia.
Roslyn J FrancisMedical School, University of Western Australia, Perth, WA, Australia.
Girish DwivediHarry Perkins Institute of Medical Research, Murdoch, WA, Australia. girish.dwivedi@perkins.uwa.edu.au.ORCID 0000-0003-0717-740X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLingering inflammation after COVID-19 has been proposed as a contributor to long-term cardiovascular risk, yet the link between pulmonary and vascular inflammation remains insufficiently defined. This study aimed to quantify residual lung and vascular inflammation in individuals recovered from mild-to-moderate COVID-19 using ¹⁸F-FDG PET/CT and assess their association.

methodsFifty-nine participants underwent ¹⁸F-FDG PET/CT imaging at a median of 97 days (IQR: 77-112.5) following clinical recovery from COVID-19. Lung inflammation was assessed using standardised uptake value maximum (SUV

resultsCompared with controls, individuals post-COVID-19 exhibited significantly elevated SUV

conclusionPersistent pulmonary inflammation is evident following mild-to-moderate COVID-19 and is associated with increased vascular inflammation. These findings suggest a mechanistic link between post-infectious lung and vascular inflammation, potentially contributing to elevated cardiovascular risk. ¹⁸F-FDG PET/CT enabled sensitive detection of subclinical inflammation in both compartments, highlighting the value of quantitative PET metrics in elucidating systemic inflammatory response following viral infection.

Indexed as

Cardiovascular DiseasesCOVID-19Fluorodeoxyglucose F18LungPositron Emission Tomography Computed TomographyAdultAgedFemaleHumansInflammationMaleMiddle AgedRadiopharmaceuticalsSurvivorsFluorodeoxyglucose F18RadiopharmaceuticalsCOVID-19FDG PET/CTLung inflammationSystemic inflammationTotal lung glycolysisVascular inflammation

Identifiers

PMID41286124
PMCPMC13013189

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.