Evidence map›Paper›PMID 41286161›Full record

ArticleCommunications biology2025

Cannabinoids shift the basal ganglia microRNA m

Chioma M Okeoma, Lakmini S Premadasa, Chen S Tan, Ionita C Ghiran, Mahesh Mohan

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Chioma M OkeomaDepartment of Pathology, Microbiology & Immunology, New York Medical College, Valhalla, NY, USA. cokeoma@nymc.edu.ORCID http://orcid.org/0000-0001-7737-6493
Lakmini S PremadasaSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA.
Chen S TanDivision of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Ionita C GhiranDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. ighiran@bidmc.harvard.edu.ORCID http://orcid.org/0000-0001-6655-3298
Mahesh MohanSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA. mmohan@txbiomed.org.ORCID http://orcid.org/0000-0003-4360-3277

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Texas Developmental Center for AIDS ResearchP30AI161943 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI RICE, ANDREW P · 2021 to 2025
$8.3M
Epigenetic mechanisms underlying cannabinoid modulation of neuroinflammation in HIV/SIV infection-supplementR01DA052845 · NIDA · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI BYRAREDDY, SIDDAPPA N, MOHAN, MAHESH · 2020 to 2024
$4.0M
Effect of methodological and biological variability on molecular profiling of extracellular vesicles in cancer detectionR01CA218500 · NCI · NORTHEASTERN UNIVERSITY · PI GHIRAN, IONITA CALIN, IVANOV, ALEXANDER R. · 2018 to 2022
$4.0M
Cannabinoid modulation of EV composition and function in HIV/SIV infectionR01DA050169 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI MOHAN, MAHESH, OKEOMA, CHIOMA M · 2019 to 2023
$3.8M
The effect of HIV and cocaine abuse on semen exosome composition and functionR01DA042348 · NIDA · UNIVERSITY OF IOWA · PI OKEOMA, CHIOMA M · 2016 to 2020
$2.7M
Integrative, multi-parametric characterization of the EV surface protein and nucleic acid landscape by nano-flow and sorting cytometryUH3TR002881 · NCATS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GHIRAN, IONITA CALIN, JONES, JENNIFER · 2021 to 2022
$1.9M
Characterizing the physicochemical properties of membraneless condensates and its regulation by delta-9-tetrahydrocannabinol in HIV/SIV infection.R33DA053643 · NIDA · NEW YORK MEDICAL COLLEGE · PI Mahesh Mohan, Chioma M Okeoma · 2023 to 2026
$1.3M
Antibody-based eradication of HIV from the CNS reservoirsR33MH112360 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TAN, CHEN SABRINA · 2019 to 2021
$1.3M
Significant upgrade and expansion of the Southwest National Primate Research Center Pathology UnitS10OD028732 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI KAUSHAL, DEEPAK · 2020 to 2020
$489k
Dual Beckman Coulter DxH 690T and Beckman Coulter DxH 560 ALS10OD032443 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI TURNER, JOANNE · 2022 to 2022
$86k
NCATS NIH HHS UH3 TR002881NCI NIH HHS R01 CA218500NIAID NIH HHS P30 AI161943NIDA NIH HHS R01 DA042348NIDA NIH HHS R01 DA050169NIDA NIH HHS R01 DA052845NIDA NIH HHS R33 DA053643NIH HHS P51 OD011133NIH HHS S10 OD028732NIH HHS S10 OD032443NIMH NIH HHS R33 MH112360U.S. Department of Health & Human Services | National Institutes of Health (NIH) P30AI161943U.S. Department of Health & Human Services | National Institutes of Health (NIH) P51OD111033U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01CA218500U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01DA042348U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01DA050169U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01DA052845U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01TR218500U.S. Department of Health & Human Services | National Institutes of Health (NIH) R21/R33DA053643U.S. Department of Health & Human Services | National Institutes of Health (NIH) S10OD028732U.S. Department of Health & Human Services | National Institutes of Health (NIH) S10OD032443U.S. Department of Health & Human Services | National Institutes of Health (NIH) UH3TR002881
6 · The paper itself

Abstract

Epitranscriptomic modifications [N6-methyladenosine (m

Indexed as

AdenosineAnti-Inflammatory AgentsBasal GangliaCannabinoidsMicroRNAsSimian Acquired Immunodeficiency SyndromeAnimalsMacaca mulattaMaleMethylationPhenotypeSimian Immunodeficiency VirusAdenosineAnti-Inflammatory AgentsCannabinoidsMicroRNAsN-methyladenosine

Identifiers

PMID41286161
PMCPMC12644866

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.