Evidence map›Paper›PMID 41286769›Full record

ArticleBMC palliative care2025

Acceptability of supporting lay-carer administration of anticipatory subcutaneous medications at home: a qualitative study using the theoretical framework of acceptability.

David Sunkersing, Leila Shepherd, Calandra Feather, Ivor Williams, Imogen Eastwood, Joanne Droney, Bryony Dean Franklin, Bee Wee, Lisa O'Hara, Ara Darzi and 1 more

Abstract read
In one paragraph

Article in BMC palliative care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David SunkersingImperial College London, London, UK. d.sunkersing@imperial.ac.uk.
Leila ShepherdImperial College London, London, UK.
Calandra FeatherImperial College London, London, UK.
Ivor WilliamsImperial College London, London, UK.
Imogen EastwoodCentral and North West London NHS Foundation Trust, London, UK.
Joanne DroneyImperial College London, London, UK.
Bryony Dean FranklinImperial College Healthcare NHS Trust, London, UK; UCL School of Pharmacy, London, UK.
Bee WeeOxford University Hospitals NHS Foundation Trust, Oxford, UK.
Lisa O'HaraSussex Community NHS Foundation Trust, Sussex, UK.
Ara DarziImperial College London, London, UK.
Kate GraileyImperial College London, London, UK.

Funding

Oak Foundation OFIL-20-279
6 · The paper itself

Abstract

backgroundGlobally, evidence indicates that most people prefer to receive care and die at home, provided high-quality care is available. However, systemic and logistical challenges often prevent this outcome. Palliate is a nurse-led intervention aiming to address these barriers, supporting lay-carers in administering end-of-life subcutaneous medications to their loved ones, through training, written guidance, and documentation.

aimTo explore the perceptions and experiences of patients, carers, and healthcare professionals regarding the acceptability of the Palliate intervention, using the Theoretical Framework of Acceptability (TFA), including perceived barriers and opportunities to its implementation.

methodsA qualitative study was conducted using semi-structured interviews with healthcare professionals, patients, carers, and policy-makers, informed by the TFA. Data were analysed thematically using deductive analysis.

resultsThirty participants, including people with a diagnosis of advanced illness, carers, and a range of healthcare professionals involved in end-of-life care, provided perspectives on the acceptability of the intervention in end-of-life care. Participants described potential benefits, including improved symptom management, reduced waiting times for medication, and increased empowerment for families to support care at home. Concerns were raised about carer burden, emotional responsibility, and the need for professional oversight. Some participants spoke from direct experience of administering or supporting the intervention in practice, providing insights into both its practical value and the challenges of implementation.

conclusionWhile the Palliate intervention was generally viewed as acceptable and potentially beneficial, its broader implementation requires careful consideration. Its acceptability was conditional on carers receiving clear training, ongoing professional support, and being able to participate voluntarily. These findings offer new insights into the boundaries of lay caregiving and have implications for the implementation of family-administered end-of-life care within health systems. Further research is needed to evaluate its safety, impact, and feasibility in diverse contexts before wider adoption can be recommended.

Indexed as

CaregiversHome Care ServicesPatient Acceptance of Health CareAdultAgedAged, 80 and overFemaleHumansInjections, SubcutaneousInterviews as TopicMaleMiddle AgedPalliative CareQualitative ResearchTerminal CareHuman centred designInnovationPalliative CarePerson centred careQualitative Research

Identifiers

PMID41286769
PMCPMC12750559

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.