Evidence map›Paper›PMID 41286771›Full record

ArticleBMC medicine2025

A hypothetical intervention analysis for the effects of healthy dietary patterns on reducing major chronic diseases and mortality associated with air pollutant mixtures.

Guzhengyue Zheng, Lan Chen, Shanshan Ran, Shengtao Wei, Kin Fai Ho, Zhenhe Huang, Hui Shi, Peng Hu, Ge Chen, Hualiang Lin

Abstract read
In one paragraph

Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Guzhengyue Zheng *School of Medicine, Xizang Minzu University, Xianyang, 712082, China.
Lan Chen *Department of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China.
Shanshan RanDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China.
Shengtao WeiDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China.
Kin Fai HoJC School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, 999077, China.
Zhenhe HuangDepartment of Geriatric Medicine, Affiliated Nanshan Hospital of Shenzhen University, Shenzhen, 518051, China.
Hui ShiDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China.
Peng HuDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China.
Ge ChenDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China.
Hualiang LinDepartment of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, 510080, China. linhualiang@mail.sysu.edu.cn.

Funding

National Natural Science Foundation of China 82373534State Key Research and Development Program of China 2022YFC2305305
6 · The paper itself

Abstract

backgroundRandomized trials have not assessed how changing dietary patterns affects air pollution-related chronic diseases and mortality. We estimated these risks under hypothetical dietary interventions.

methods17,254 UK Biobank adults with repeated 24-h dietary assessments (2009-2012) were included. Exposures to six air pollutants (PM

resultsOver 12.9 median follow-up years, 2295 CVD, 475 diabetes, 1912 cancer, 969 CKD, 395 COPD, 405 dementia cases, and 814 deaths occurred. Increased adherence to ten dietary patterns (excluding the healthy low-carbohydrate diet) reduced air pollution-related disease risks, with maximal benefit at optimal adherence. For example, comparing interventions targeting dietary diversity score with non-intervention, the 13-year RD (per 1000 population) ranged from - 0.48 to - 2.14 for CVD, - 2.85 to - 10.16 for diabetes, - 0.65 to - 2.95 for cancer, - 4.26 to - 16.22 for CKD, - 2.79 to - 9.60 for COPD, - 3.64 to - 12.12 for dementia, and - 2.54 to - 9.84 for death.

conclusionsInterventions optimizing dietary patterns could mitigate the 13-year risks of major chronic diseases and mortality linked to air pollutant mixtures. Adherence to healthy dietary patterns holds significant public health potential for preventing air pollution-related morbidity and premature death.

Indexed as

Air PollutantsAir PollutionDiet, HealthyAdultAgedCardiovascular DiseasesChronic DiseaseEnvironmental ExposureFemaleHumansMaleMiddle AgedNeoplasmsUnited KingdomAir PollutantsAir pollutionChronic diseasesDietary patternsHypothetical intervention analysisMortalityParametric g-formula

Identifiers

PMID41286771
PMCPMC12642279

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.