Who was studied, and how
One number in the abstract
Where each one falls
Where it lands on the map
What it changes
Among 10 other studies
54,972people with cardiovascular disease, in this paper
The trial randomly assignedassigned by chance
semaglutide (oral or subcutaneous)
placebo
Reduced deaths−15%
randomisedthe abstract, start to end
… all-cause mortality (relative risk (RR) 0.85; 95% CI 0.79 to 0.91; I …
← favours treatmentfavours comparator →
could be chanceAll-cause mortalitysemaglutide (oral or subcutaneous) vs placebo
RR 0.850.79–0.91
GLP-1 receptor agonistsAll-cause mortality
GLP-1 receptor agonists × all-cause mortalityhelps?replicated
unlikelylikely
0.88not counted
← favours treatmentfavours comparator →
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