Evidence map›Paper›PMID 41286949›Full record

ReviewJournal of ovarian research2025

RNA sequencing in ovarian cancer research: a comprehensive review.

Fang Shen, Chan Li, Yue Li, Ying Shen, Fengjuan Han

Abstract readReview
In one paragraph

Review in Journal of ovarian research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fang ShenHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Chan LiHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Yue LiHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Ying ShenThe First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China.
Fengjuan HanThe First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China. hanfengjuan2004@163.com.ORCID http://orcid.org/0000-0002-5953-3608

Funding

National Natural Science Foundation of China 82274566
6 · The paper itself

Abstract

As a highly fatal and heterogeneous disease, ovarian cancer (OC) lacks sufficient treatment choices. Over the past decade, RNA sequencing (RNA-seq) has profoundly changed research methods in molecular biology, enabling comprehensive analysis of transcriptomes, somatic mutations, and tumour heterogeneity. In OC research, the application of RNA-seq technologies has significantly enhanced scientists' understanding of the biological mechanisms underlying the disease, providing deeper insights into the intrinsic mechanisms of key processes such as tumour initiation, metastasis progression, drug resistance formation, and immune evasion. This breakthrough not only expands our understanding of OC but also holds promise for the discovery of novel diagnostic biomarkers, the development of innovative therapies, and the establishment of precise prognostic assessment systems. This review summarizes RNA-seq technologies and their applications in OC research, while also discussing the challenges and opportunities for their broader implementation in cancer studies.

Indexed as

Ovarian NeoplasmsSequence Analysis, RNABiomarkers, TumorFemaleHumansBiomarkers, TumorApplicationOvarian cancerRNA sequencingTranscriptomics

Identifiers

PMID41286949
PMCPMC12751439

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.