Evidence map›Paper›PMID 41287485›Full record

ArticleJournal of Korean medical science2025

Risk of Pelvic Insufficiency Fractures in Cervical Cancer Survivors: Using the National Claim Database.

Ki-Tae Park, Jung-Wee Park, Ye Jin Jeon, Jean Kyung Bak, Bit-Na Yoo, Youn Kyung Chung, Byung-Ho Yoon, Young-Kyun Lee

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ki-Tae Park *Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0002-7305-9447
Jung-Wee Park *Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0002-4515-1895
Ye Jin JeonDepartment of Public Health, Graduate School, Yonsei University, Seoul, Korea.ORCID https://orcid.org/0000-0002-3780-5668
Jean Kyung BakNational Evidence-Based Healthcare Collaborating Agency (NECA), Seoul, Korea.ORCID https://orcid.org/0000-0002-8763-5580
Bit-Na YooNational Evidence-Based Healthcare Collaborating Agency (NECA), Seoul, Korea.ORCID https://orcid.org/0000-0001-6217-6798
Youn Kyung ChungCenter for Gynecologic Cancer, National Cancer Center, Goyang, Korea.ORCID https://orcid.org/0000-0001-8224-8306
Byung-Ho YoonDepartment of Orthopedic Surgery, Ewha Womans University College of Medicine, Seoul, Korea. cragy0215@naver.com.ORCID https://orcid.org/0000-0001-8518-6331
Young-Kyun LeeDepartment of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0001-6564-4294

Funding

Ministry of Health and Welfare HI18C0284Ministry of Health and Welfare NS21-004
6 · The paper itself

Abstract

backgroundCervical cancer, one of the most prevalent cancers among women worldwidely, has seen improved survival rates due to advancements in pelvic radiation therapy (RT). Several risk factors for pelvic insufficiency fracture (PIF) have been reported in patients with cervical cancer. This study aimed to estimate the incidence of PIFs in patients with cervical cancer and assess the potential risk factors for PIF using a national claim database.

methodsA total of 13,480 cervical cancer patients were identified during 2007 to 2016 from linkage between the Korea National Health Insurance Service and Korea Central Cancer Registry. Patients were identified and divided into PIF and non-PIF groups. The incidence of PIFs was estimated and risk factors for PIFs, including age, type of medical institution, residential area, insurance type, Surveillance, Epidemiology, and End Results summarized stage, RT and comorbidities, were assessed using multivariate Cox proportional hazards regression analysis.

resultsIn a cohort of 13,480 patients diagnosed with cervical cancer, PIF occurred in 134 (1.0%). Among the variables, older age (adjusted hazard ratio [aHR], 1.063; 95% confidence interval [CI], 1.047-1.079;

conclusionThe incidence of PIFs in cervical cancer survivors was 1.0% in this national claim database study and it demonstrated that RT and older age were significantly associated with an increased risk of PIF. Our findings suggest that clinicians should be aware of the risk of PIF, especially in older patients who underwent RT.

Indexed as

Fractures, StressPelvic BonesUterine Cervical NeoplasmsAdultAgedCancer SurvivorsDatabases, FactualFemaleHumansIncidenceMiddle AgedProportional Hazards ModelsRepublic of KoreaRisk FactorsCervical CancerKoreaNational Claim DatabasePelvic Insufficiency FractureRadiation Therapy

Identifiers

PMID41287485
PMCPMC12643958

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.