ArticleCureus2025
Clinical Outcomes of Acute Viral Lower Respiratory Infections in Hospitalized Children.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Pathogen and Patient Characteristics and the Severity of Viral Respiratory Infections in Children.JAMA network open · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundViral infections represent a significant global health strain in children who are below the age of five years. Among these, lower respiratory tract infections (LRTIs) pose a higher risk, particularly in children with comorbid conditions. However, less is known about the impact of LRTIs on healthy children. This academic discourse aims to explore this gap by looking into the clinical outcomes of viral LRTIs in hospitalized children without comorbidities.
objectiveThe objective of this study was to investigate whether the clinical outcomes of healthy children below the age of five years hospitalized as a result of viral LRTIs differed depending on the presence of single or multiple viral pathogens.
methodsWe carried out a monocentric retrospective study of 646 children below the age of five years who were admitted for LRTIs at Woodhull Medical and Mental Health Center, New York City, NY, between January 1, 2021, and December 31, 2023. Inclusion and exclusion criteria were applied to select healthy children with no significant medical history. Assessment of statistics was performed using IBM SPSS Statistics software, version 29.0 (IBM Corp., Armonk, NY), to study the clinical outcomes of focus, which included the requirement of a high-flow nasal cannula (HFNC) and other respiratory support, the need for transfer or ICU admission, and the length of hospital stay.
conclusionIn healthy children below the age of five years hospitalized with viral LRTIs, multiple viral infections were associated with more severe outcomes, including longer duration of hospitalization and a higher likelihood of PICU transfer. These findings call attention to the importance of considering viral co-infections in predicting disease severity and guiding clinical management, even in children with no risk factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.