ArticleCellular and molecular life sciences : CMLS2025
The contrasting effects of two antimalarial drugs on insulin secretion.
Jing Lu, Fengran Xiong, Qianrui Zhang, Ruxuan Zhao, Chenyang Zhang, Gang Wei, Jinkui Yang
Abstract read
In one paragraphArticle in Cellular and molecular life sciences : CMLS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Jing Lu *Department of Endocrinology, Beijing Diabetes Institute, Beijing Key Laboratory of Diabetes Research and Care, Beijing Tongren Hospital, Capital Medical University, Beijing, China. jinglu_tr@ccmu.edu.cn.ORCID http://orcid.org/0000-0001-6744-7833 Fengran Xiong *Department of Endocrinology, Beijing Diabetes Institute, Beijing Key Laboratory of Diabetes Research and Care, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Qianrui ZhangDepartment of Endocrinology, Beijing Diabetes Institute, Beijing Key Laboratory of Diabetes Research and Care, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Ruxuan ZhaoDepartment of Endocrinology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Chenyang ZhangDepartment of Endocrinology, Beijing Diabetes Institute, Beijing Key Laboratory of Diabetes Research and Care, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Gang WeiDepartment of Endocrinology, Beijing Diabetes Institute, Beijing Key Laboratory of Diabetes Research and Care, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Jinkui YangDepartment of Endocrinology, Beijing Diabetes Institute, Beijing Key Laboratory of Diabetes Research and Care, Beijing Tongren Hospital, Capital Medical University, Beijing, China. jkyang@ccmu.edu.cn.
Funding
Beijing Tongren Hospital Seed Funds 2022-YJJ-ZZL-046Cultivation Fund of Capital Medical University PYZ23107National Natural Science Foundation of China 82470900，82070890Natural Science Foundation of Beijing Municipality 7232230
6 · The paper itselfAbstract
Quinolines and artemisinins are the two most important antimalarial drugs worldwide. In addition to antimalarial effects, quinine has been extensively documented to directly stimulate insulin secretion, potentially causing hypoglycemia in malaria patients undergoing treatment through the inhibition of K
Indexed as
AntimalarialsArtemisininsInsulinInsulin SecretionQuinineAnimalsArtemetherCalciumGlucoseInsulin-Secreting CellsIslets of LangerhansMaleMiceMice, Inbred C57BLQuinolinesAntimalarialsArtemetherArtemisininsCalciumGlucoseInsulinQuinineQuinolinesArtemisininsGlucoseInsulin secretionKCNH6 potassium channelQuinolines
Identifiers
PMID41288707
PMCPMC12647422
What Socratic holds
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