Evidence mapPaperPMID 41288927Full record

ArticleDermatology and therapy2026

Efficacy and Safety of a Drinkable Nutraceutical in Premenopausal Women with Telogen Effluvium: A 6-Month, Randomized, Multicenter, Double-Blind, Placebo-Controlled Study.

Claudia Bernárdez, Sebastian Podlipnik, Gillian E Westgate, Ralf Paus, Laura Zamfir, Daniela Grohmann, Manuel Sáez Moya

Registry-linked trialAbstract read
In one paragraph

Article in Dermatology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07111312 (Placebo-controlled, Parallel, Randomized), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07111312 nacompletednot on this map

Placebo-controlled, Parallel, Randomized (1:1), Double-blind Study Over 6 Months to Evaluate the Efficacy and Safety of the Food Supplement Olistic Women.

TypeinterventionalSponsorOlistic Research Labs S.L.Ran2023 to 2025Enrolled106ConditionsTelogen EffluviumArmsDrinkable multifactorial food supplement containing vitamins, minerals, plant extracts, and other bioactive compounds, formulated to support hair growth and scalp health in women., Placebo control
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Claudia BernárdezClínica AB Derma, Madrid, Spain.
Sebastian PodlipnikDepartment of Dermatology, Hospital Clínic de Barcelona, University of Barcelona, IDIBAPS, Barcelona, Spain.
Gillian E WestgateGill Westgate Consultancy Ltd, Stevington, UK.
Ralf PausDr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Laura ZamfirOlistic Research Labs S.L., Travessera de Gràcia, 17-21, 08021, Barcelona, Spain.
Daniela GrohmannOlistic Research Labs S.L., Travessera de Gràcia, 17-21, 08021, Barcelona, Spain.
Manuel Sáez MoyaOlistic Research Labs S.L., Travessera de Gràcia, 17-21, 08021, Barcelona, Spain. manuel.saez@olisticscience.com.ORCID http://orcid.org/0009-0006-1293-4822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHair loss is a multifactorial and complex condition influenced by hormonal changes, nutritional deficiencies, genetic predisposition, oxidative stress, aging, inflammation, and psychological stress. This 6-month study evaluated the hair growth-promoting efficacy and safety of a drinkable nutraceutical (Olistic

methodsA total of 106 premenopausal female subjects (18-40 years) clinically diagnosed with telogen effluvium were randomized in a double-blind manner into the active (n = 53) or placebo (n = 53) arm, taking 1 vial (25 mL) per day for 6 months. The primary endpoint was the increase in hair density from baseline versus placebo assessed by phototrichoscopy using TrichoScan

resultsDaily oral supplementation with the active product was well tolerated and resulted in a statistically significant increase in hair density versus placebo at day 90 (17.53 ± 2.46 vs 9.56 ± 2.43 hairs/cm

conclusionThe tested nutraceutical showed a statistically significant increase in hair density and A:C/T ratio compared to placebo over 6 months in premenopausal women with telogen effluvium. These results not only support efficacy and safety of the tested nutraceutical but also that a multifactorial nutraceutical approach can effectively manage telogen effluvium in premenopausal women.

trial registrationClinicalTrials.gov identifier, NCT07111312 (retrospectively registered 07/2025).

Indexed as

Anagen-to-catagen/telogen ratioFood supplementHair densityHair growthHair loss

Identifiers

PMID41288927
PMCPMC12872997

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.