ArticleOpen biology2025
Monitoring extracellular vesicle surface glyco-properties using fluorescent lectins and nanoparticle tracking analysis.
Article in Open biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Engineering Strategies for Plant-Derived Extracellular Vesicles: Modification, Drug Delivery Performance, and Synergistic Effects with Gel Composite Systems.Pharmaceutics · 2026Review
- Glycosylation of Extracellular Vesicles: Analytical and Translational Insights into Biomarker Discovery and Regenerative Medicine.International journal of molecular sciences · 2026Review
- Monitoring extracellular vesicle surface glyco-properties using fluorescent lectins and nanoparticle tracking analysis.Open biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Extracellular vesicles are small particles released by all cell types. Different extracellular vesicle isolation methods are widely used, yet none achieve an optimal balance between yield, purity and structural integrity. This study aimed to establish a comparative approach for evaluating different extracellular vesicle preparations using nanoparticle tracking analysis. A simple one-step assay relying on fluorescence-based nanoparticle tracking analysis was used to evaluate lectin binding to extracellular vesicles as a measure of possible changes in their surface glycosylation during various isolation methods. Seminal extracellular vesicles were isolated from normozoospermic men using ultracentrifugation alone-UC-sEVs-or combined with size exclusion chromatography-UC-SEC-sEVs-or microfiltration-UC-MF-sEVs. They were analysed based on their size and lectin-binding properties using wheat germ agglutinin and
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.